Results 141 to 150 of about 3,054,711 (370)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Estimation of combining ability for selection of Triticum aestivum L. genotypes with some yield related traits [PDF]

open access: yesCommunications in Plant Sciences, 2015
Combining ability analysis was studied in 2013-2014 a line × tester with six lines and three testers of wheat. Genetic variability among genotypes was assessed for plant height, days to heading, days to maturity, number of tillers per plant, number of ...
Babar Ijaz   +3 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Heterosis and combining ability for yield and other agronomic traits in Triticale

open access: yesOpen Agriculture, 2018
The estimation of genetic parameters such as heterosis (Mh), heterobeltiosis (Hh), general combining ability (GCA) and specific combining ability (SCA) allows inferences about the predominant action of the genes, indicates the appropriate selection ...
Ferrari Enzo   +3 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Heterosis and combining ability studies in single cross hybrids synthesized with diverse inbred lines of maize (Zea mays L.)

open access: yesElectronic Journal of Plant Breeding, 2018
Combining ability and heterosis analysis were performed in ten lines, five testers and their fifty hybrid combinations of maize using line x tester analysis.
G. Nandhitha   +2 more
doaj   +1 more source

Specific and General Combining Abilities for Production and Reproduction among Lines of Holstein Cattle

open access: yesJournal of Dairy Science, 1979
Abstract Six inbred lines of Holstein cattle were developed and reciprocally crossed to assess the importance of heterotic effects for yield and reproductive traits. Overall both yield and reproductive performance declined with inbreeding, but effects varied with different lines. In two of the lines milk yield increased during inbreeding.
T.M. Ludwick   +4 more
openaire   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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