Results 121 to 130 of about 11,516,984 (249)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Comprehensive study on combining ability, heritability and genetic advance for important morphological and biochemical traits in bread wheat (Triticumaestivum L.)

open access: yesDiscover Agriculture
In this study, 15 genetically diverse wheat genotypes (10 lines and 5 testers) and their 50 F₁ hybrids were evaluated using a randomized design for 13 morphological and 2 biochemical traits under normal environmental conditions.
Anand Kumar   +9 more
doaj   +1 more source

Improving forecast accuracy by combining recursive and rolling forecasts [PDF]

open access: yes
This paper presents analytical, Monte Carlo, and empirical evidence on the effectiveness of combining recursive and rolling forecasts when linear predictive models are subject to structural change. We first provide a characterization of the bias-variance
Todd E. Clark, Michael W. McCracken
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Combining Ability for Yield and Associated Characters in Rice

open access: yes
Combining ability for yield and several related traits in rice (Oryza sativa L.), with a major focus on panicle characteristics, were studied in a 15 ✕ 15 diallel cross (excluding reciprocals). Eleven of the 15 parent cultivars were semidwarfs with broad
Shrivastava, M.N., Seshu, D.V.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Combining ability in eight selected clones of sugarcane (Saccharum sp)

open access: yesCrop Breeding and Applied Biotechnology, 2002
Eight commercial sugarcane (Saccharum sp) clones were crossed in a full diallel. Five characters were evaluated in the progeny in one or two harvests: Refractometer solids (Brix %), Yield (tons of cane per hectare, TCH), number of millable stalks ...
José Antonio Bressiani   +4 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Heterotic potential and combining ability of Coffea arabica L

open access: yesScientific Reports
The use of hybrid vigor or heterosis in Coffea arabica L. cultivation has gradually been commercially explored worldwide since research has evolved in understanding this phenomenon and the vegetative propagation techniques or male-sterility making its ...
Vinícius Teixeira Andrade   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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