Results 111 to 120 of about 11,516,984 (249)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Griffing's methods comparison for general and specific combining ability in cucumber. [PDF]

ScientificWorldJournal, 2012
Olfati JA, Samizadeh H, Rabiei B, Peyvast G.   +3 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Evaluation of combining ability and genetic analysis for salinity tolerance in a 7 × 7 F1 half-diallel population of groundnut (Arachis hypogaea L.)

Discover Plants
A study was conducted at the net house of Sher-e-Bangla Agricultural University in Dhaka to develop salt-tolerant and high-yielding groundnut genotypes.
Md. Akram Hossain Chowdhury, Md. Shahidur Rashid Bhuiyan, Md. Shah-E-Alam, Md. Sarowar Hossain, Md. Fazlul Karim, Shahanaz Parveen, Md. Harun-Ur-Rashid   +6 more
doaj   +1 more source

Combining ability analysis in mungbean [Vigna radiata(L.) Wilczek]

, 2017
A diallel method was employed in which eight genotypically diverse lines of mungbean were crossed among themselves in all possible combinations excluding reciprocals.
S. R. Maloo, Rajani Verma, R. B. Dubey, Anamika Nath, Baudh Bharti   +4 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Assessment of combining ability for grain yield and its attributing traits in maize (Zea mays L.)

Discover Agriculture
A comprehensive understanding of combining ability is an emerging focus in hybrid maize research in Nepal. The present study aimed to evaluate the performance of single-cross maize hybrids and to estimate the combining abilities of parental lines for ...
Jiban Shrestha, Surya Kant Ghimire, Krishna Hari Dhakal, Mahendra Prasad Tripathi   +3 more
doaj   +1 more source

COMBINING ABILITY STUDIES FOR QUANTITATIVE TRAITS IN BRASSICA JUNCEA

, 2020
Combining ability was determined in an 8 × 8 F1 diallel cross of Brassica juncea L. genotypes for various quantitative traits during 2010-2011 at the University of Agriculture, Peshawar, Pakistan.
S Ali, S Gul, K Naveed, N U Khan, N Ali, M Saeed, Farhatullah   +6 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source