Results 151 to 160 of about 3,193,780 (374)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Evaluation of general and specific combining ability of bread wheat quantitative traits in normal and moisture stress conditions [PDF]

, 2005
Gholam Abbas Moosavi, B Yazdi Samadi, A. Zali, M. R. Ghannadha   +3 more
openalex   +1 more source

Daya Gabung Dan Heterosis Karakter Vegetatif, Generatif, Dan Daya Hasil Jarak Pagar (Jatropha Curcas L.) Menggunakan Analisis Dialel [PDF]

, 2015
General Combining Ability (GCA) and Specific Combining Ability(SCA) are important in creating high yielding varieties. A parent havinghigh GCA is appropriate to produce synthetic or composite varieties, whilehigh SCA is to produce hybrid.
HARTATI, R. S. (RR), SUDARSONO, S. (SUDARSONO)   +1 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

GENERAL AND SPECIFIC COMBINING ABILITY OF GROWTH PERFORMANCE ATTRIBUTES IN RABBITS [PDF]

Egyptian Journal of Rabbit Science, 2021
Kariman Farg, Gouda Gouda, Hasan Elkelawy, Mostafa Tawfeek   +3 more
openaire   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Evaluation of combining ability and genetic analysis for salinity tolerance in a 7 × 7 F1 half-diallel population of groundnut (Arachis hypogaea L.)

Discover Plants
A study was conducted at the net house of Sher-e-Bangla Agricultural University in Dhaka to develop salt-tolerant and high-yielding groundnut genotypes.
Md. Akram Hossain Chowdhury, Md. Shahidur Rashid Bhuiyan, Md. Shah-E-Alam, Md. Sarowar Hossain, Md. Fazlul Karim, Shahanaz Parveen, Md. Harun-Ur-Rashid   +6 more
doaj   +1 more source

HETEROSIS AND COMBINING ABILITY IN INTER-SPECIFIC HYBRIDS BETWEEN CMS OF Bajra AND NAPIER GRASS [PDF]

, 1995
AMIRTHA DEVARATHINAM A
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Combining ability analysis for yield and its components in groundnut (Arachis hypogaea L.) [PDF]

Electronic Journal of Plant Breeding, 2010
Combining ability was studied among 24 crosses involving eight lines and three testers. The general andspecific combining ability variances were highly significant for all the characters studied.
A.Mothilal and A. Ezhil*
doaj