Results 231 to 240 of about 3,193,780 (374)

General and Specific Combining Ability Analysis for Quantitative Characters in Tunisian Spring Barley

, 2016
Sana Medimagh, Mouldi El Felah, Mohamed El Gazzah   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Research on genetic characteristics of corolla pattern traits in <i>Sinningia speciosa</i>. [PDF]

Front Plant Sci
Hao Y.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Vesicular Stomatitis Virus-Based Oncolytic Virotherapy: Recent Progress and Emerging Trends. [PDF]

Curr Oncol
Catacalos-Goad C, Johnstone C, Grdzelishvili VZ.   +2 more
europepmc   +1 more source

General and specific combining ability studies for leaf area in some maize inbreds in agroecological conditions of Kosovo

, 2008
S. Aliu, Š. Fetahu, L. Rozman, A. Salillari   +3 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Harnessing artificial intelligence for the assessment of liver fibrosis and steatosis <i>via</i> multiparametric ultrasound. [PDF]

World J Gastroenterol
Viceconti N, Andaloro S, Paratore M, Miliani S, D'Acunzo G, Cerniglia G, Mancuso F, Melita E, Gasbarrini A, Riccardi L, Garcovich M.   +10 more
europepmc   +1 more source

General and specific combining ability effects and variances for fruit yield and its contributing traits in Okra (Abelmoschus esculentus (L.) Moench) [PDF]

, 2019
Monika Punia, Garg Dk
openalex  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source