Results 81 to 90 of about 2,693,058 (333)
Estimation of In-Process Power Consumption in Face Milling by Specific Energy Consumption Models
International Journal of Automation Technology, 2020 Prediction of energy consumption in the entire production system is crucial for managing production and pursuing environmentally friendly manufacturing. One critical issue that must be addressed to realize green manufacturing is to construct a method for predicting the electric power consumed by each manufacturing device.
Tetsuo Samukawa +2 more
openaire +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
A survey of energy saving techniques for mobile computers [PDF]
, 1997 Portable products such as pagers, cordless and digital cellular telephones, personal audio equipment, and laptop computers are increasingly being used. Because these applications are battery powered, reducing power consumption is vital. In this report we
Havinga, Paul J.M., Smit, Gerard J.M.
core +3 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Modeling and Energy Consumption of Unilateral Heating Process of Flat Wood Details
Drvna Industrija, 2017 A methodology has been suggested for mathematical modeling and research of two mutually connected problems: the temperature distribution along the thickness of flat wood details subjected to unilateral heating and the energy consumption of this process ...
Nencho Deliiski +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2003 The problem of finding what direction cracks should move is not completely solved. A commonly accepted way to predict crack directions is by computing the density of elastic potential energy stored well away from the crack tip, and finding a direction of
Broberg K. B. +6 more
core +2 more sources