Results 121 to 130 of about 8,961,128 (255)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
, 1963 The relationship of specific heat of canine blood to hematocrit and density was determined at 37.46 C. Density is seen to give the better index of this property. The equation describing the relationship is: specific heat = 0.998 – 2.30 (specific gravity
Maurice B. Visscher +3 more
core +1 more source
Applied SciencesFreezing time stands out as the most critical parameter in ice cream production, significantly influencing the final product’s quality and production efficiency.
Ömer Alp Atici, Derya Burcu Özkan
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Specific Heat of Mn-doped NaxCoO2 � yH2O
, 2012 [[abstract]]C(T) of NaxCo0.99Mn0.01O2 yH2O is studied to reveal more details on the nature of the doped Mn ions and the Tc suppression. The extra specific heat contribution in NaxCo0.99Mn0.01O2 yH2O manifests the induced local magnetic moment due to ...
Lin, J. Y. ; Chen, Y. J. ; Liu, Chia-Jyi; Wang, J. S. ; Sun, C. P. ; Yang, H. D.
core
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
, 2001 If not designed and installed properly in a suitable location, heat pumps can produce noise at nuisance levels for adjacent residents. Various (national and international) systems and guidelines used for measuring, predicting and regulating noise levels ...
Eggenschwiler, Kurt (author) +1 more
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source