Results 121 to 130 of about 2,535,115 (299)
Health Technology Assessment, 2011 Background: Breast cancer is the most common type of cancer in women. Evaluation of axillary lymph node metastases is important for breast cancer staging and treatment planning.
KL Cooper +9 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
THE BEST CUES EVOLVE WITH MEMORY: A NEW CHALLENGE FOR THE ENCODING SPECIFICITY HYPOTHESIS [PDF]
openThe Encoding Specificity Hypothesis, a cornerstone in memory research, posits that the successful recollection of an event is cue dependent and relies on the degree of match between cues present at retrieval and encoding conditions.
DELMARCO, MATTIA
core
Robustness and specificity in object detection
, 2004 In this paper, we discuss the role of robustness to geometric conformity versus specificity in machine learning. The key observation made here is that object variation due to appearance and due to geometric deformation are often, for good reasons ...
Åström, Karl +7 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Demographic and cultural specificity and integration of migrants
, 2001 'Dieser Workshop sammelte und diskutierte Forschungsdesigns, Instrumente bzw. Frageboegen zum Migrations-/ Integrations-Komplex, um den Grundstein fuer eine vergleichende demographische Forschung zu legen - nachdem Bevoelkerungsfragen ins Zentrum ...
Bundesinstitut fuer Bevoelkerungsforschung -BIB-, Wiesbaden (Germany)
core
Evaluating the specificity of community injury hospitalization data over time
, 2016 This study identified the areas of poor specificity in national injury hospitalization data and the areas of improvement and deterioration in specificity over time.
Kirsten Vallmuur +3 more
core +1 more source