Results 131 to 140 of about 2,080,270 (249)

How Interviewees Determine What Interviewers Want to Know. [PDF]

Int Rev Soc Psychol
Neequaye DA, Lorson A, Barnett HK.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Maxillary sinus-related adverse event reports associated with endosseous dental implants in the FDA MAUDE database: a retrospective text-mining analysis. [PDF]

BMC Oral Health
Liu C, Tang T, Chen Y, Meng X, Song Z, Liu D, Zhu L.   +6 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Diagnostic accuracy of tachypnoea for predicting mortality and identifying sepsis in young infants aged 0-59 days: a systematic review and meta-analysis. [PDF]

BMJ Paediatr Open
Widyaningsih SA, Driker S, Fung A, Schmeck N, Mathias S, Yu M, Shafiq Y, Hoey A, Kehoe T, Kim Y, Adnan J, Hussaini AS, Wade CG, Lee AC.   +13 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Prediction of antibody non-specificity using protein language models and biophysical parameters. [PDF]

MAbs
Sakhnini LI, Beltrame L, Fulle S, Sormanni P, Henriksen A, Lorenzen N, Vendruscolo M, Granata D.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cost-effectiveness of community tuberculosis screening in South Africa. [PDF]

Am J Respir Crit Care Med
Deleger JN, Khatami SN, Jones M, Jalali MS, Paltiel AD, Wong EB, Florance G, Freedberg KA, Wood R, Horsburgh CR, Reddy KP.   +10 more
europepmc   +1 more source