Results 181 to 190 of about 4,678,205 (343)

Clinical and cost-effectiveness of detailed anomaly ultrasound screening in the first trimester: a mixed-methods study

Health Technology Assessment
Background In the United Kingdom, pregnant women are offered two scans: at 11–14 and 18–20 weeks’ gestation. Current guidance supports fetal anatomical screening at the second scan, but evidence suggests earlier detection is possible.
Jehan N Karim, Helen Campbell, Pranav Pandya, Edward C F Wilson, Zarko Alfirevic, Trish Chudleigh, Elizabeth Duff, Jane Fisher, Hilary Goodman, Lisa Hinton, Christos Ioannou, Edmund Juszczak, Louise Linsell, Heather L Longworth, Kypros H Nicolaides, Anne Rhodes, Gordon Smith, Basky Thilaganathan, Jim Thornton, Gillian Yaz, Oliver Rivero-Arias, Aris T Papageorghiou   +21 more
doaj   +1 more source

Developing the inclusive curriculum: Is supplementary lecture recording an effective approach in supporting students with Specific Learning Difficulties (SpLDs)?

, 2018
Karl P. Nightingale, Vikki Anderson, Susan Onens, Qulsom Fazil, Helen Davies   +4 more
openalex   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Etiology-specific incidence and mortality of diarrheal diseases in the African region: a systematic review and meta-analysis [PDF]

Cecilie Thystrup, Shannon E. Majowicz, Dinaol Belina Kitila, Binyam Negussie Desta, Olanrewaju Emmanuel Fayemi, Christianah Idowu Ayolabi, Ephrasia Hugho, Elna M. Buys, Gabriel Bidemi Akanni, Norgia Elsa Machava, Celso Monjane, Tine Hald, Sara M. Pires   +12 more
openalex   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Electronic Versus Paper-Based Assessment of Health-Related Quality of Life Specific to HIV Disease: Reliability Study of the PROQOL-HIV Questionnaire [PDF]

, 2014
Martin Duracinský, Christophe Lalanne, Cécile Goujard, S. Herrmann, C. Cheung-Lung, Jean-Paul Brosseau, Y. Schwartz, Olivier Chassany   +7 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A firm-specific Malmquist productivity index model for stochastic data envelopment analysis: an application to commercial banks [PDF]

Alireza Amirteimoori, Tofigh Allahviranloo, Maryam Nematizadeh   +2 more
openalex   +1 more source

The Role of Movement-Specific Reinvestment in Visuomotor Control of Walking by Older Adults [PDF]

, 2018
Liis Uiga, Catherine M. Capio, Donghyun Ryu, William R. Young, Mark Wilson, Thomson W. L. Wong, Andy C. Y. Tse, Rich S.W. Masters   +7 more
openalex   +1 more source