Results 81 to 90 of about 142,258 (356)

Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition

open access: yesJournal of Cell Science, 2019
Although the formation of RNA-protein bodies has been studied intensively, their mobility and how their number and size are regulated are still poorly understood.
Jiah Kim   +4 more
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Convolutional Neural Network and Guided Filtering for SAR Image Denoising

open access: yesRemote Sensing, 2019
Coherent noise often interferes with synthetic aperture radar (SAR), which has a huge impact on subsequent processing and analysis. This paper puts forward a novel algorithm involving the convolutional neural network (CNN) and guided filtering for SAR ...
Shuaiqi Liu   +6 more
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Statistical Properties of an Unassisted Image Quality Index for SAR Imagery

open access: yesRemote Sensing, 2019
The M estimator is a recently proposed image-quality index used to evaluate the despeckling operation in SAR (Synthetic Aperture Radar) data. It is used also to rank despeckling filters and to improve their design.
Luis Gomez   +2 more
doaj   +1 more source

Harnessing speckle for a sub-femtometre resolved broadband wavemeter and laser stabilization [PDF]

open access: yesNature Communications, 2017
The accurate determination and control of the wavelength of light is fundamental to many fields of science. Speckle patterns resulting from the interference of multiple reflections in disordered media are well-known to scramble the information content of
N. K. Metzger   +7 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Choosing a laser for laser speckle contrast imaging

open access: yesScientific Reports, 2019
The use of laser speckle contrast imaging (LSCI) has expanded rapidly for characterizing the motion of scattering particles. Speckle contrast is related to the dynamics of the scattering particles via a temporal autocorrelation function, but the quality ...
D. Postnov   +3 more
semanticscholar   +1 more source

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