Results 41 to 50 of about 352 (140)

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, Volume 13, Issue 52, 18 September 2026.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source

First description of the baubellum in the spectacled bear Tremarctos ornatus (Mammalia: Ursidae)

Journal of Anatomy
AbstractThe baubellum (os clitoridis) is a bone found in the clitoris of many female eutherian mammals and is homologous to the baculum in males. In contrast to the baculum, the baubellum has received very little attention regarding its morphological or interspecific diversity, or on hypotheses for its function.
De Ridder, Tim, Goossenaerts, Ellen, Spruyt, Jonas, Van Ginneken, Chris, Aerts, Peter, Maclaren, James   +5 more
openaire   +3 more sources

Data gaps and heterogeneity limit our understanding of human–wildlife interactions: A continental study of Andean bears

People and Nature
The expansion and intensification of human activities have increased interactions between people and wildlife. Interactions involving bears and other large carnivores are complex and can lead to conflicts. Promoting positive coexistence requires managing
Roxana Rojas‐VeraPinto, Rubén Bernardo‐Madrid, Manuela González‐Suarez   +2 more
doaj   +1 more source

Quantitative assessment of masticatory muscles based on skull muscle attachment areas in Carnivora

The Anatomical Record, Volume 309, Issue 9, Page 2368-2394, September 2026.
Abstract Masticatory muscles are composed of the temporalis, masseter, and pterygoid muscles in mammals. Each muscle has a different origin on the skull and insertion on the mandible; thus, all masticatory muscles contract in different directions. Collecting in vivo data and directly measuring the masticatory muscles anatomically in various Carnivora ...
Kai Ito, Mugino O. Kubo, Ryo Kodera, Sei‐ichiro Takeda, Hideki Endo   +4 more
wiley   +1 more source

Focal Cortical Dysplasia Type II: Somatic Mutations, Molecular Mechanisms, and Integrative Multi‐Omics Framework

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Focal cortical dysplasia Type II (FCD II) is a major cause of drug‐resistant epilepsy and is commonly associated with somatic brain mutations in the PI3K–AKT–mTOR pathway. The timing, cell lineage, and spatial distribution of somatic variants influence lesion formation.
Zesheng Li, Yihe Wang, Jianwei Shi, Yumin Luo, Yongzhi Shan, Guoguang Zhao   +5 more
wiley   +1 more source

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

Characterization of Ovarian Cell Types and Molecular Signatures in Mauremys reevesii Using Single‐Cell Sequencing

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
This study employed single‐cell transcriptomics to identify six major cell types in the Mauremys reevesii ovary. Except for an unknown cell group, five cell types, including oocytes, granulosa cells, fibroblasts, immune cells, and endothelial cells, were characterized with specific marker genes.
Kaiqi Yuan, Xin Niu, Yue Yuan, Jiale Zhou, Meiling Hong, Li Ding   +5 more
wiley   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, Volume 13, Issue 45, 13 August 2026.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Molecular population genetic analysis of the spectacled bear (Tremarctos ornatus) in the northern Andean area [PDF]

Hereditas, 2003
Eighty-two Andean bear samples obtained in three South American Andean countries were analyzed using five hypervariable microsatellite markers. Neither the overall sample nor the samples coming from each of the countries analyzed were in Hardy-Weinberg equilibrium.
openaire   +2 more sources

Hábitos alimentarios del Puma concolor (Carnivora: Felidae) en el Parque Nacional Natural Puracé, Colombia

Revista de Biología Tropical, 2011
La dieta de Puma concolor es ampliamente conocida a lo largo de su distribución, sin embargo, en Colombia no se ha realizado ningún estudio sobre sus hábitos alimentarios.
Andrés Hernández-Guzmán, Esteban Payán, Octavio Monroy-Vilchis   +2 more
doaj