Results 91 to 100 of about 2,857,129 (284)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Images and Spectra of the 2017 Total Solar Eclipse Corona From Our Oregon Site

Frontiers in Astronomy and Space Sciences, 2018
We report on early results from a suite of instruments for imaging and spectra we deployed to Salem, Oregon, for 2 min of totality at the August 21, 2017, total solar eclipse.
Jay M. Pasachoff, Christian Lockwood, Erin Meadors, Ross Yu, Cielo Perez, Marcos A. Peñaloza-Murillo, Daniel B. Seaton, Aris Voulgaris, Ron Dantowitz, Vojtech Rušin, Thanasis Economou   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modification of the transmission spectrum of the ”semiconductor-dielectric” photonic crystal in an external magnetic field

Advanced Electromagnetics, 2017
In this paper, some features of electromagnetic transmission of the waves of ”semiconductor dielectric” periodic Bragg structure with a finite number of periods have been investigated.
S. V. Eliseeva, I. V. Fedorova, D. I. Sementsov   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Spectra

, 2020
The Spectra Technology name of the project coordinated by Paolo Pelini is a new spectrometry technology that promises to give excellent results at low cost. The first laboratory tests comfort us in having identified molecular spectra of various molecules which if confirmed by further tests will open the way to an innovative technology.
Svatopluk Civiš, Ekaterina Zanozina, Adam Pastorek, Petr Kubelík, Martin Ferus, Ashok Chilukoti   +5 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

MODELS OF HAMILTONIAN AND LOW-FREQUENCY SPECTRA OF COLLECTIVE EXCITATIONS IN SPIN S = 1 MAGNETICS

East European Journal of Physics, 2017
The paper studies the dynamic description of non-equilibrium processes in single-sublattice and multisublattice magnets with the spin s=1. In case of magnets with the spin s=1 and SU(3) symmetry of the exchange interaction, there are eight magnetic ...
A. V. Glushchenko, M. Y. Kovalevsky
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source