Results 81 to 90 of about 2,300,127 (311)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Images and Spectra of the 2017 Total Solar Eclipse Corona From Our Oregon Site
We report on early results from a suite of instruments for imaging and spectra we deployed to Salem, Oregon, for 2 min of totality at the August 21, 2017, total solar eclipse.
Jay M. Pasachoff +10 more
doaj +1 more source
Thom spectra that are symmetric spectra
We analyze the functorial and multiplicative properties of the Thom spectrum functor in the setting of symmetric spectra and we establish the relevant homotopy invariance.
openaire +3 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
In this paper, some features of electromagnetic transmission of the waves of ”semiconductor dielectric” periodic Bragg structure with a finite number of periods have been investigated.
S. V. Eliseeva +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
MODELS OF HAMILTONIAN AND LOW-FREQUENCY SPECTRA OF COLLECTIVE EXCITATIONS IN SPIN S = 1 MAGNETICS
The paper studies the dynamic description of non-equilibrium processes in single-sublattice and multisublattice magnets with the spin s=1. In case of magnets with the spin s=1 and SU(3) symmetry of the exchange interaction, there are eight magnetic ...
A. V. Glushchenko, M. Y. Kovalevsky
doaj
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

