Results 91 to 100 of about 27,875,543 (317)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Image depth estimation assisted by multi-view projection

Complex & Intelligent Systems
In recent years, deep learning has significantly advanced the development of image depth estimation algorithms. The depth estimation network with single-view input can only extract features from a single 2D image, often neglecting the information ...
Liman Liu, Jinshan Tian, Guansheng Luo, Siyuan Xu, Chen Zhang, Huaifei Hu, Wenbing Tao   +6 more
doaj   +1 more source

Spectral Analysis Implies Spectral Synthesis

Mathematics
In this paper we show that spectral analysis implies spectral synthesis for arbitrary varieties on locally compact Abelian groups that have no discrete subgroups of an infinite torsion-free rank.
László Székelyhidi
doaj   +1 more source

Making Laplacians commute [PDF]

, 2013
In this paper, we construct multimodal spectral geometry by finding a pair of closest commuting operators (CCO) to a given pair of Laplacians. The CCOs are jointly diagonalizable and hence have the same eigenbasis.
Bronstein, Michael M., Glashoff, Klaus, Loring, Terry A.   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

LOCAL FITS OF SIGNALS WITH ASYMPTOTIC BRANCHES

Odessa Astronomical Publications, 2017
The method of "asymptotic parabola" fit is described, its analytical properties are discussed in comparison with other types of fits. The method is effective for the (possibly highly asymmetric) signals with practically linear ascending and descending ...
V. I. Marsakova, I. L. Andronov
doaj   +1 more source

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

Nature, 2017
The organization of the eukaryotic cell into discrete membrane-bound organelles allows for the separation of incompatible biochemical processes, but the activities of these organelles must be coordinated.
A. Valm, Sarah Cohen, W. Legant, Justin Melunis, Uri Hershberg, Eric Wait, Andrew R. Cohen, M. Davidson, E. Betzig, J. Lippincott-Schwartz   +9 more
semanticscholar   +1 more source

Semiclassical and spectral analysis of oceanic waves

, 2011
In this work we prove that the shallow water flow, subject to strong wind forcing and linearized around an adequate stationary profile, develops for large times closed trajectories due to the propagation of Rossby waves, while Poincar\'e waves are shown ...
Cheverry, Christophe, Gallagher, Isabelle, Paul, Thierry, Saint-Raymond, Laure   +3 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on defect type in eddy-current testing based on phase spectrum analysis

The Journal of Engineering, 2019
This article proposes the use of phase angle gradient as a feature to detect and classify different types of defects. Based on the principle of eddy-current testing (ECT), the ECT platform was designed and manufactured.
Ronghua Zhang, Song Ye
doaj   +1 more source