Results 141 to 150 of about 24,551,019 (389)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

EEG Power and Functional Connectivity Correlates with Semantic Long-Term Memory Retrieval

open access: yesIEEE Access, 2018
In this paper, we investigated the relationships between EEG and semantic long-term memory retrieval using spectral analysis and functional connectivity.
Samer Hanouneh   +3 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Detecting Confounding in Multivariate Linear Models via Spectral Analysis

open access: yesJournal of Causal Inference, 2018
We study a model where one target variable Y$Y$ is correlated with a vector X:=(X1,…,Xd)$\textbf{X}:=(X_1,\dots,X_d)$ of predictor variables being potential causes of Y$Y$.
Janzing Dominik, Schölkopf Bernhard
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Seismic performance of buckling‐restrained brace outrigger system in various configurations

open access: yesJapan Architectural Review, 2019
The outrigger system is deemed an effective solution for mitigating the seismic responses of tall core‐tube‐type buildings. By incorporating a buckling‐restrained brace (BRB) in the outrigger system (BRB‐outrigger), the BRB‐outrigger reduces seismic ...
Pao‐Chun Lin, Toru Takeuchi
doaj   +1 more source

Complex spectral analysis and test function spaces [PDF]

open access: yes, 2014
We consider complex eigenstates of unstable Hamiltonian and its physically meaningful regions. Starting from a simple model of a discrete state interacting with a continuum via a general potential, we show that its Lippmann-Schwinger solution set can be ...
Kim, Sungyun
core  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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