Results 51 to 60 of about 24,551,019 (389)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Expression of PEI-coated gold nanoparticles carrying exogenous gene in periwinkle mesophyll cells and its practice in huanglongbing research

iScience, 2022
Summary: Huanglongbing (HLB) is a devastating disease of citrus, which is mostly caused by Candidatus Liberibacter asiaticus (CLas). To realize the specific application of nano-transgenic technology in HLB, AuNPs-PEI (Gold Nanoparticles-Polyethylenimine)
Junzhe Zhang, Wenxue Lei, Yixuan Meng, Chengqian Zhou, Baihong Zhang, Jun Yuan, Min Wang, Dongqing Xu, Xiangchun Meng, Wenli Chen   +9 more
doaj  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Knowledge Transfer Between Artificial Intelligence Systems

Frontiers in Neurorobotics, 2018
We consider the fundamental question: how a legacy “student” Artificial Intelligent (AI) system could learn from a legacy “teacher” AI system or a human expert without re-training and, most importantly, without requiring significant computational ...
Ivan Y. Tyukin, Ivan Y. Tyukin, Alexander N. Gorban, Alexander N. Gorban, Konstantin I. Sofeykov, Konstantin I. Sofeykov, Ilya Romanenko   +6 more
doaj   +1 more source

Differentiable Measures for Speech Spectral Modeling

IEEE Access, 2022
Autoregressive models for the envelope of speech power spectral densities (PSDs) are refined by the self-supervised spectral learning machine (S3LM) provided with differentiable spectral objective functions, including the Itakura-Saito divergence (ISD ...
Miguel Arjona Ramirez, Wesley Beccaro, Demostenes Zegarra Rodriguez, Renata Lopes Rosa   +3 more
doaj   +1 more source

Spectral Analysis Program (SAP) [PDF]

, 1973
Program eliminates or reduces time-consuming aspects of computation of power spectrum for high-frequency communication system.
Detchmendy, D. M., Hayden, W. L.
core   +1 more source

Spectral Analysis of Polysomnography in Narcolepsy [PDF]

Psychiatry Investigation, 2017
This study was conducted to identify differences between people with narcolepsy and the normal control of delta and theta activity using electroencephalogram (EEG) spectrum analysis of nocturnal polysomnography (PSG).Seven narcolepsy patients and seven age-sex matched normal controls underwent PSG and multiple sleep latency tests.
Wan Seok Seo, Ho Dong Choi, Seok Ho Yun
openaire   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

eLife
Autophagy-related gene 6 (ATG6) plays a crucial role in plant immunity. Nonexpressor of pathogenesis-related genes 1 (NPR1) acts as a signaling hub of plant immunity. However, the relationship between ATG6 and NPR1 is unclear.
Baihong Zhang, Shuqin Huang, Shuyu Guo, Yixuan Meng, Yuzhen Tian, Yue Zhou, Hang Chen, Xue Li, Jun Zhou, Wenli Chen   +9 more
doaj   +1 more source

Data analysis techniques: Spectral processing [PDF]

, 1983
The individual steps in the data processing scheme applied to most radars used for wind sounding are analyzed. This processing method uses spectral analysis and assumes a pulse Doppler radar.
Strauch, R. G.
core   +1 more source