Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
GlycoSLASH: Concurrent Glycopeptide Identification from Multiple Related LC-MS/MS Data Sets by Using Spectral Clustering and Library Searching. [PDF]
Li S, Zhu J, Lubman DM, Zhou H, Tang H.
europepmc +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers of <i>C9orf72</i>. [PDF]
Bruffaerts R +31 more
europepmc +1 more source
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou +6 more
wiley +1 more source
Spectral clustering identifies patterns of chiropractic care in a national longitudinal cohort. [PDF]
Ray M, Fang SY, Lisi AJ, Romano PS.
europepmc +1 more source
Acoustic Emission Signal Characterisation of Failure Mechanisms in CFRP Composites Using Dual-Sensor Approach and Spectral Clustering Technique. [PDF]
Šofer M +5 more
europepmc +1 more source
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper +7 more
wiley +1 more source
Spectral Clustering with Likelihood Refinement for High-Dimensional Latent Class Recovery. [PDF]
Lyu Z, Gu Y.
europepmc +1 more source
Corrigendum: Spectral Clustering Algorithm for Cognitive Diagnostic Assessment. [PDF]
Guo L, Yang J, Song N.
europepmc +1 more source

