Results 111 to 120 of about 1,145,296 (299)

Longitudinal forced harmonic vibrations of vertical rods with concentrated mass.

Вестник Дагестанского государственного технического университета: Технические науки
Objective. Longitudinal forced harmonic vibrations of vertical rods with a concentrated mass at the end are considered.Method. The mathematical model of forced kinematically excited longitudinal vibrations is described by a differential equation and ...
H. P. Kulterbaev, M. M. Payzulaev
doaj   +1 more source

High-Frequency Tails in Spectral Densities

The Journal of Physical Chemistry A
Recent advances in numerically exact quantum dynamics methods have brought the dream of accurately modeling the dynamics of chemically complex open systems within reach. Path-integral-based methods, hierarchical equations of motion (HEOM) and quantum analog simulators all require the spectral density (SD) of the environment to describe its effect on ...
Roman Korol, Xinxian Chen, Ignacio Franco   +2 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Spectral density classification for environment spectroscopy

Machine Learning: Science and Technology
Spectral densities encode the relevant information characterizing the system–environment interaction in an open-quantum system problem. Such information is key to determining the system’s dynamics.
J Barr, G Zicari, A Ferraro, M Paternostro   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Darboux transformation for the discrete Schrodinger equation

Electronic Journal of Differential Equations, 2019
The discrete Schrodinger equation on a half-line lattice with the Dirichlet boundary condition is considered when the potential is real valued, is summable, and has a finite first moment.
Tuncay Aktosun, Abdon E. Choque-Rivero, Vassilis G. Papanicolaou   +2 more
doaj  

Testing temporal constancy of the spectral structure of a time series

, 2010
Statistical inference for stochastic processes with time-varying spectral characteristics has received considerable attention in recent decades. We develop a nonparametric test for stationarity against the alternative of a smoothly time-varying spectral ...
Paparoditis, Efstathios
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Spectral densities and diagrams of states of one-dimensional ionic Pauli conductor

Condensed Matter Physics, 2011
We focus on the features of spectra and diagrams of states obtained via exact diagonalization technique for finite ionic conductor chain in periodic boundary conditions.
O. Vorobyov, I.V. Stasyuk, R.Ya. Stetsiv
doaj   +1 more source