Results 81 to 90 of about 1,145,296 (299)

Short-range correlations in asymmetric nuclear matter

, 2003
The spectral function of protons in the asymmetric nuclear matter is calculated in the self-consistent T-matrix approach. The spectral function per proton increases with increasing asymmetry.
Akmal, Baldo, Baldo, Benhar, Benhar, Benhar, Bożek, Bożek, Bożek, Bożek, Brockmann, Brueckner, Dewulf, Dewulf, Dickhoff, Dickhoff, Frick, Frick, Jeukenne, Kadanoff, Mahaux, Müther, Müther, Müther, P. Bożek, Rohe, Ryckebuch, Van Neck, Wiringa   +28 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Recent Advances in the Calculation of Dynamical Correlation Functions

Frontiers in Physics, 2020
We review various theoretical methods that have been used in recent years to calculate dynamical correlation functions of many-body systems. Time-dependent correlation functions and their associated frequency spectral densities are the quantities of ...
J. Florencio, O. F. de Alcantara Bonfim
doaj   +1 more source

Neutrino spectral density at electroweak scale temperature

, 2013
Motivated by the scenario of resonant leptogenesis in which lepton number creation in the electroweak-scale is relevant, we investigate the spectral properties and possible collective nature of the standard model neutrinos at electroweak scale ...
Hidaka, Yoshimasa, Kunihiro, Teiji, Miura, Kohtaroh, Satow, Daisuke   +3 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Spectral analysis of oscillatory wind wave parameters in fetch-limited deep-water conditions at a small reservoir and their prediction: Case Study of the Hulín Reservoir in the Czech Republic

Journal of Hydrology and Hydromechanics
The dams and banks of small water reservoirs face significant erosion from wind-generated oscillatory waves. Proper design of structure height is crucial to protect such banks against erosion, considering the maximum characteristics of wind waves.
Kotaška Stanislav, Duchan David, Pelikán Petr, Špano Miroslav   +3 more
doaj   +1 more source

A Statistical and Spectral Model for Representing Noisy Sounds with Short-Time Sinusoids

EURASIP Journal on Advances in Signal Processing, 2005
We propose an original model for noise analysis, transformation, and synthesis: the CNSS model. Noisy sounds are represented with short-time sinusoids whose frequencies and phases are random variables.
Myriam Desainte-Catherine, Pierre Hanna   +1 more
doaj   +1 more source

Fundamental Limits of Low-Density Spreading NOMA with Fading

, 2018
Spectral efficiency of low-density spreading non-orthogonal multiple access channels in the presence of fading is derived for linear detection with independent decoding as well as optimum decoding.
Di Benedetto, Maria-Gabriella, Ferrante, Guido Carlo, Le, Mai T. P., Quek, Tony Q. S.   +3 more
core   +1 more source