Results 81 to 90 of about 193,376 (261)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

On the spectral efficiency of a sphere [PDF]

open access: yes, 2004
In many cases it is desired to have both high capacity and small antennas in wireless communication systems. Unfortunately, the antenna performance deteriorate when the antennas get electrically small. In this paper fundamental limitations from antenna theory and broadband matching are used to analyze the spectral eciency of an arbitrary antenna ...
Gustafsson, Mats, Nordebo, Sven
openaire  

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Parallel Quadrature Spatial Modulation for Massive MIMO Systems With ICI Avoidance

open access: yesIEEE Access, 2019
Despite its efficiency in conventional multiple-input multiple-output (MIMO) wireless systems, quadrature spatial modulation (QSM) becomes less efficient in massive MIMO systems since it does not adapt to the number of antennas but always uses one or two
Guosheng Huang   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Enhancing the Coexistence of LTE and Wi-Fi in Unlicensed Spectrum Through Convolutional Neural Networks

open access: yesIEEE Access, 2019
Over the last years, the ever-growing wireless traffic has pushed the mobile community to investigate solutions that can assist in more efficient management of the wireless spectrum.
Vasilis Maglogiannis   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Performance Analysis of Cooperative Quadrature Spatial Modulation System With Hybrid Decode-Amplify-Forward Relaying Protocol

open access: yesIEEE Access
This paper introduces the cooperative quadrature spatial modulation (CQSM) system with hybrid decode-amplify-forward (HDAF) relaying protocol. Compered with the traditional CQSM system which only uses amplify-and-forward (AF) protocol and decode-and ...
Xiangyan Bu, Ke Pang
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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