Results 141 to 150 of about 92,516 (310)

Finite Element Approximations for a linear Cahn-Hilliard-Cook equation driven by the space derivative of a space-time white noise [PDF]

, 2012
We consider an initial- and Dirichlet boundary- value problem for a linear Cahn-Hilliard-Cook equation, in one space dimension, forced by the space derivative of a space-time white noise.
Zouraris, Georgios, Kossioris, Georgios
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Handling geometric singularities by the mortar spectral element method for fourth-order problems

Electronic Journal of Differential Equations, 2017
This article concerns the numerical analysis and the error estimate of the biharmonic problem with homogeneous boundary conditions using the mortar spectral element method in domains with corners. Since the solution of this problem can be written as a
Mohamed Abdelwahed, Nejmeddine Chorfi, Vicentiu Radulescu   +2 more
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Implementation of the spectral element discretization of the nonstationary velocity–vorticity–pressure Stokes formulation

Boundary Value Problems
This paper deals with the resolution of the time-dependent velocity–vorticity–pressure formulation of Stokes problem in a two- and three-dimensional domain. The discretization is based on the spectral element method with respect to the space variable and
Nejmeddine Chorfi, Henda Ouertani
doaj   +1 more source

A robust fault detection method of rolling bearings using modulation signal bispectrum analysis

, 2015
Envelope analysis is a widely used method for bearing fault detection. To obtain high detection accuracy, it is critical to select an optimal narrowband for envelope demodulation.
Gu, Fengshou, Rehab, Ibrahim, Ball, Andrew, Tian, Xiange, Abdalla, Gaballa   +4 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Calculation of normal mode spectra in laterally heterogeneous earth models using an iterative direct solution method,

Normal mode observations play an important role in studying broad-scale lateral variations in the Earth. Such studies require the calculation of accurate synthetic spectra in realistic earth models, and this remains a computationally challenging problem.
Deuss, Arwen, Woodhouse, John H, Al‐Attar, David   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source