Results 41 to 50 of about 232,364 (309)

Unquenched flavor and tropical geometry in strongly coupled Chern-Simons-matter theories [PDF]

open access: yes, 2011
We study various aspects of the matrix models calculating free energies and Wilson loop observables in supersymmetric Chern-Simons-matter theories on the three-sphere.
A Kapustin   +38 more
core   +2 more sources

First Hyper Zagreb Spectral Radii of Splitting and Shadow Graphs

open access: yesScientific Annals of Computer Science
The spectral radius RS of graph G is a spectral invariant derived from the eigenvalues of the associated matrix for a graph G. It is widely used in fields such as computer science, chemistry, biology, and network analysis.
Ahmad Bilal, Muhammad Mobeen Munir
doaj   +1 more source

Infinite Lewis Weights in Spectral Graph Theory

open access: yesCoRR, 2023
We study the spectral implications of re-weighting a graph by the $\ell_\infty$-Lewis weights of its edges. Our main motivation is the ER-Minimization problem (Saberi et al., SIAM'08): Given an undirected graph $G$, the goal is to find positive normalized edge-weights $w\in \mathbb{R}_+^m$ which minimize the sum of pairwise \emph{effective-resistances}
Amit Suliman, Omri Weinstein
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A New Family of Graphs and Strong Antireciprocal Eigenvalue Property

open access: yesJournal of Mathematics
Spectral graph theory explores the relationship between the eigenvalues and the structural properties of graphs. This study focuses on the fundamental matrices associated with simple graphs, specifically the adjacency matrix. This work contributes to the
Sadia Akhter   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Bounding first-order quantum phase transitions in adiabatic quantum computing

open access: yesPhysical Review Research, 2023
In the context of adiabatic quantum computation (AQC), it has been argued that first-order quantum phase transitions (QPTs) due to localization phenomena cause AQC to fail by exponentially decreasing the minimal spectral gap of the Hamiltonian along the ...
Matthias Werner   +2 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

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