Results 101 to 110 of about 711,060 (330)

Modal characterization of the ASCIE segmented optics testbed: New algorithms and experimental results [PDF]

open access: yes
New frequency response measurement procedures, on-line modal tuning techniques, and off-line modal identification algorithms are developed and applied to the modal identification of the Advanced Structures/Controls Integrated Experiment (ASCIE), a ...
Aubrun, Jean-Noel, Carrier, Alain C.
core   +1 more source

IGR J22517+2218=MG3 J225155+2217: a new gamma-ray lighthouse in the distant Universe

open access: yes, 2007
We report on the identification of a new soft gamma ray source, namely IGR J22517+2218, detected with IBIS/INTEGRAL. The source, which has an observed 20-100 keV flux of ~4 x10^-11 erg cm-2 s-1, is spatially coincident with MG3 J225155+2217, a quasar at ...
A. Bazzano   +10 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Interstellar Detection of O-protonated Carbonyl Sulfide, HOCS+

open access: yesThe Astrophysical Journal
We present the first detection in space of O-protonated carbonyl sulfide (HOCS ^+ ), in the midst of an ultradeep molecular line survey toward the G+0.693-0.027 molecular cloud. From the observation of all K _a = 0 transitions ranging from J _lo = 2 to J
Miguel Sanz-Novo   +14 more
doaj   +1 more source

Random splicing assisted deep learning for breast cancer cell line classification via Raman spectroscopy

open access: yesComputational and Structural Biotechnology Journal
Raman spectroscopy extracts rich biochemical information on a single cell, demonstrating significant potential for precise cancer identification. While machine learning enhances spectral analysis efficiency, conventional models remain constrained by data
Yiheng Liu   +5 more
doaj   +1 more source

EPR of Cu\u3csup\u3e2+\u3c/sup\u3e Prion Protein Constructs at 2 GHz Using the \u3cem\u3eg\u3c/em\u3e\u3csub\u3e⊥\u3c/sub\u3e Region to Characterize Nitrogen Ligation [PDF]

open access: yes, 2009
A double octarepeat prion protein construct, which has two histidines, mixed with copper sulfate in a 3:2 molar ratio provides at most three imidazole ligands to each copper ion to form a square-planar Cu2+ complex.
Antholine, William E.   +5 more
core   +1 more source

Spectroscopic Constants, Abundances, and Opacities of the TiH Molecule

open access: yes, 2004
Using previous measurements and quantum chemical calculations to derive the molecular properties of the TiH molecule, we obtain new values for its ro-vibrational constants, thermochemical data, spectral line lists, line strengths, and absorption ...
A. Burrows   +8 more
core   +1 more source

Spectral Characterization of Copper and Iron Sulfide Combustion: A Multivariate Data Analysis Approach for Mineral Identification on the Blend

open access: yesMetals, 2019
The pyrometallurgical processes for primary copper production have only off-line and time-demanding analytical techniques to characterize the in and out streams of the smelting and converting steps.
Walter Díaz   +6 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

On the Abiotic Origin of Dimethyl Sulfide: Discovery of Dimethyl Sulfide in the Interstellar Medium

open access: yesThe Astrophysical Journal Letters
Following the discovery of dimethyl sulfide (DMS; CH _3 SCH _3 ) signatures in comet 67P/Churyumov–Gerasimenko, we report the first detection of this organosulfur species in the interstellar medium during the exploration of an ultradeep molecular line ...
Miguel Sanz-Novo   +16 more
doaj   +1 more source

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