Results 81 to 90 of about 119,847 (263)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Rail Transit Radiation Source Identification Method Based on Enhanced Diagonal Integral Bispectrum

Chengshi guidao jiaotong yanjiu
[Objective] Numerous external interference signals exist in urban rail transit wireless communication system, posing a significant threat to operational safety.
Haichuan LIU, Kexin ZHANG, Hui HUI, Lu WEN   +3 more
doaj   +1 more source

Spectral Line Identification in Photoionized Silicon Plasma Emission.

Proposed for presentation at the 2021 SSAP symposium - virtual held February 16 - January 18, 2021 in albuquerque, NM., 2021
Patricia Cho, Guillaume Loisel, James Bailey, Taisuke Nagayama, Stephanie Hansen, Christopher Fontes, Michael Montgomery, Donald Winget   +7 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Quest for Sulfur-bearing Refractory Species: Identification of CaS in the Interstellar Medium

The Astrophysical Journal Letters
The recent detection of refractory molecules in massive star-forming regions provides a means of probing the innermost regions of disks around massive stars.
A. Tasa-Chaveli, Á. Sánchez-Monge, A. Fuente, A. Ginsburg, H. S. P. Müller, T. Möller, P. Rivière-Marichalar, D. Navarro-Almaida, G. Esplugues, P. Schilke, M. Rodríguez-Baras, S. Thorwirth, L. Beitia-Antero   +12 more
doaj   +1 more source

SPECTRAL AND PHOTOMETRIC STUDIES OF MRK6 AND MRK1040 IN THE OPTICAL RANGE

Eurasian Physical Technical Journal
This paper is dedicated to the study of variability in active galactic nuclei, which play a key role in understanding the physical processes occurring in their central regions.
S.A. Shomshekova, E.K. Denissyuk, L.N. Kondratyeva, A.V. Serebryanskiy, G.K. Aimanova, L. Aktay   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Persistent Homology for Parameter-free Radio Spectral Line Decomposition

The Astronomical Journal
Modern radio surveys routinely deliver millions of spectra, making automated Gaussian decomposition a critical bottleneck in extracting physical insight about the interstellar medium.
Carlos Vera-Ciro
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source