Results 71 to 80 of about 497,177 (252)
Determination of alloy content from plume spectral measurements [PDF]
The mathematical derivation for a method to determine the identities and amounts of alloys present in a flame where numerous alloys may be present is described.
Madzsar, George C.
core +1 more source
Estimating stellar oscillation-related parameters and their uncertainties with the moment method
, 2005 The moment method is a well known mode identification technique in asteroseismology (where `mode' is to be understood in an astronomical rather than in a statistical sense), which uses a time series of the first 3 moments of a spectral line to estimate ...
Aerts C. +8 more
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Spectral atlases of the Sun from 3980 to 7100 {\AA} at the center and at the limb
, 2014 In this work, we present digital and graphical atlases of spectra of both the solar disk-center and of the limb near the Solar poles using data taken at the UTS-IAP & RIAAM (the University of Tabriz Siderostat, telescope and spectrograph jointly ...
Ajabshirizadeh, Ali +2 more
core +2 more sources
Spectral Line Identification in Photoionized Silicon Plasma Emission.
Proposed for presentation at the 2021 SSAP symposium - virtual held February 16 - January 18, 2021 in albuquerque, NM., 2021 Patricia Cho +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Modal characterization of the ASCIE segmented optics testbed: New algorithms and experimental results [PDF]
New frequency response measurement procedures, on-line modal tuning techniques, and off-line modal identification algorithms are developed and applied to the modal identification of the Advanced Structures/Controls Integrated Experiment (ASCIE), a ...
Aubrun, Jean-Noel, Carrier, Alain C.
core +1 more source