Results 51 to 60 of about 119,847 (263)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Molecular Hydrogen Line Identifications in Solar Flares Observed by IRIS: Lower Atmospheric Structure from Radiometric Analysis

open access: yesThe Astrophysical Journal
A rich spectrum of molecular hydrogen (H _2 ) emission lines is seen in sensitive observations from the far-ultraviolet (FUV) channels of the Interface Region Imaging Spectrograph (IRIS) during flare activity in solar active region NOAA Active Region ...
Sarah A. Jaeggli, Adrian N. Daw
doaj   +1 more source

Statistical Methods in the Identification and Prediction of the Solar X-Ray Spectral Lines [PDF]

open access: yesSymposium - International Astronomical Union, 1975
SummaryWith the accumulation of numerous identifications of the solar X and XUV spectral lines, the need is felt for systemizing such identification. The results are presented below.
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Maser Activity of Organic Molecules toward Sgr B2(N)

open access: yesThe Astrophysical Journal
At centimeter wavelengths, single-dish observations have suggested that the Sagittarius (Sgr) B2 molecular cloud at the Galactic Center hosts weak maser emission from several organic molecules, including CH _2 NH, HNCNH, and HCOOCH _3 . However, the lack
Ci Xue   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Revisiting Near-infrared Features of Kilonovae: The Importance of Gadolinium

open access: yesThe Astrophysical Journal
The observation of the kilonova AT2017gfo and investigations of its light curves and spectra confirmed that neutron star mergers are sites of r -process nucleosynthesis.
Salma Rahmouni   +9 more
doaj   +1 more source

On-line parameter and delay estimation of continuous-time dynamic systems

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2015
The problem of on-line identification of non-stationary delay systems is considered. The dynamics of supervised industrial processes are usually modeled by ordinary differential equations.
Kozłowski Janusz, Kowalczuk Zdzisław
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A Compact, Ultra-high-resolution Virtually Imaged Phased Array Spectrograph for Solar Spectroscopic Observations: Astrocomb Characterization and First Light

open access: yesThe Astronomical Journal
We present a compact, high-spectral-resolution prototype spectrograph based on a Virtually Imaged Phased Array (VIPA), which is designed for solar spectral observations. This fiber-fed instrument has a size of only 53 × 20 × 18 cm ^3 .
Yutao Wang   +6 more
doaj   +1 more source

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