Results 31 to 40 of about 497,177 (252)

The Broadband XMM-Newton and NuSTAR X-ray Spectra of Two Ultraluminous X-ray Sources in the Galaxy IC 342 [PDF]

, 2014
We present results for two Ultraluminous X-ray Sources (ULXs), IC 342 X-1 and IC 342 X-2, using two epochs of XMM-Newton and NuSTAR observations separated by $\sim$7 days.
Bachetti, Matteo, Barret, Didier, Boggs, Steven E., Christensen, Finn C., Craig, William W., Fabian, Andrew C., Furst, Felix, Grefenstette, Brian W., Hailey, Charles J., Harrison, Fiona A., Madsen, Kristin K., Miller, Jon M., Ptak, Andrew F., Rana, Vikram, Stern, Daniel, Walton, Dominic J., Webb, Natalie A., Zhang, William W.   +17 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

First detection of bromine and antimony in hot stars

, 2018
Bromine (atomic number Z=35) and antimony (Z=51) are extremely difficult to detect in stars. In very few instances, weak and mostly uncertain identifications of Br I, Br II, and Sb II in relatively cool, chemically peculiar stars were successful. Adopted
Knoerzer, M., Kruk, J. W., Rauch, T., Werner, K.   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Line Survey of Orion KL from 325 to 360 GHz [PDF]

, 1997
We present a high-sensitivity spectral line survey of the high-mass star-forming region Orion KL in the 325-360 GHz frequency band. The survey was conducted at the Caltech Submillimeter Observatory on Mauna Kea, Hawaii.
Blake, G. A., Groesbeck, T. D., Phillips, T. G., Schilke, P.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The N Enrichment and Supernova Ejection of the Runaway Microquasar LS 5039 [PDF]

, 2003
We present an investigation of new optical and ultraviolet spectra of the mass donor star in the massive X-ray binary LS 5039. The optical band spectral line strengths indicate that the atmosphere is N-rich and C-poor, and we classify the stellar ...
Brandt N., Claret A., Clausen J. V., Cousins A. W. J., D. R. Gies, D. W. Wingert, De Greve J. P., de Loore C., Dearborn D. S. P., Howarth I. D., Kaper L., Kaper L., Kilkenny D., L. Kaper, Lamers H. J. G. L. M., M. V. McSwain, Mathys G., Meynet G., Nelemans G., P. J. Wiita, Puls J., Ribo M., Schonberner D., Vanbeveren D., W. Huang, Wade R. A., Wellstein S., Zahn J.-P.   +27 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Unusual Spectral Energy Distribution of a Galaxy Previously Reported to be at Redshift 6.68 [PDF]

, 2000
Observations of distant galaxies are important both for understanding how galaxies form and for probing the physical conditions of the universe at the earliest epochs.
A Fernández-Soto, BP Schmidt, H-W Chen, Hsiao-Wen Chen, JA Holtzman, Kenneth M. Lanzetta, N Yahata, Noriaki Yahata, RC Puetter, Sebastian Pascarelle   +9 more
core   +2 more sources