Results 41 to 50 of about 497,177 (252)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Interpreting the Ionization Sequence in Star-Forming Galaxy Emission-Line Spectra [PDF]

open access: yes, 2016
High ionization star forming (SF) galaxies are easily identified with strong emission line techniques such as the BPT diagram, and form an obvious ionization sequence on such diagrams.
Allen, James T.   +6 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Hydrogen and helium abundances in neutron star atmospheres [PDF]

open access: yes
Identification of neutron stars by hydrogen and helium spectral line ...
Rosen, L. C.
core   +1 more source

Understanding the dynamical structure of pulsating stars. HARPS spectroscopy of the delta Scuti stars rho Pup and DX Cet

open access: yes, 2014
High-resolution spectroscopy is a powerful tool to study the dynamical structure of pulsating stars atmosphere. We aim at comparing the line asymmetry and velocity of the two delta Sct stars rho Pup and DX Cet with previous spectroscopic data obtained on
Guiglion, G.   +6 more
core   +1 more source

Spectral line identification from a photoionised silicon plasma in emission

open access: yesJournal of Plasma Physics
Next-generation X-ray satellite telescopes such as XRISM, NewAthena and Lynx will enable observations of exotic astrophysical sources at unprecedented spectral and spatial resolution. Proper interpretation of these data demands that the accuracy of the models is at least within the uncertainty of the observations.
Patricia Bo Cho   +9 more
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Spectroscopic requirements for HALOE: An analysis of the HCl and HF channels [PDF]

open access: yes
Spectral line parameters that have absorption features within the HCl and HF channels of the Halogen Occultation Experiment (HALOE) were evaluated. Line positions and identification of stratospheric and solar absorption features in both channels are ...
Harvey, G. A.   +5 more
core   +1 more source

Identification of a New $\gamma$-ray-emitting narrow-line Seyfert 1 Galaxy, at Redshift $\sim1$

open access: yes, 2015
We report on the identification of a new $\gamma$-ray-emitting narrow-line Seyfert 1 (NLS1) galaxy, SDSS J122222.55+041315.7, which increases the number of known objects of this remarkable but rare type of active galactic nuclei (AGN) to seven.
Komossa, S.   +6 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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