Results 51 to 60 of about 251,815 (286)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Stark Widths of Na IV Spectral Lines
Atoms, 2017 Sodium is a very important element for the research and analysis of astrophysical, laboratory, and technological plasmas, but neither theoretical nor experimental data on Stark broadening of Na IV spectral lines are present in the literature.
Milan S. Dimitrijević +3 more
doaj +1 more source
Broad line emission from iron K- and L-shell transitions in the active galaxy 1H 0707-495
, 2009 Since the 1995 discovery of the broad iron K-line emission from the Seyfert galaxy MCG-6-30-15 (ref. 1), broad iron K lines have been found in emission from several other Seyfert galaxies, from accreting stellar-mass black holes and even from accreting ...
T. Boller +70 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Spectral optical monitoring of a double-peaked emission line AGN Arp 102B: Variability of spectral lines and continuum⋆ [PDF]
, 2013 Context. We present results of long-term (1987–2010) optical spectral monitoring of the broad-line radio galaxy Arp 102B, a prototype of an active galactic nucleus with double-peaked broad emission lines that are commonly assumed to be emitted from an ...
Luis Carrasco Bazúa +4 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
BM ORI: SEARCH FOR SECONDARY SPECTRAL LINES
Odessa Astronomical Publications, 2017 The search for the secondary spectral lines was made by using special high signal/noise ratio emulsion A700u. The four spectra (two near elongations and two near conjunctions) were obtained with 6-m telescope (BTA), dispersion is 26 Å/mm. We searched the
V. S. Shevchenko, E. A. Vitrichenko
doaj +1 more source
Light source for producing self-reversed spectral lines
, 1962 A new light source has been developed which produces numerous self-reversed lines in both the first and second spectra of rare-earth elements. It consists of a pulsed arc discharge with a peak current of 75 amperes and an on-time of one millisecond per ...
Sugar, Jack
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source