Results 61 to 70 of about 2,504,636 (253)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Improving the Method of Measuring the Electron Density via the Asymmetry of Hydrogenic Spectral Lines in Plasmas by Allowing for Penetrating Ions

open access: yesAtoms, 2018
There was previously proposed and experimentally implemented a new diagnostic method for measuring the electron density Ne using the asymmetry of hydrogenic spectral lines in dense plasmas.
Paul Sanders, Eugene Oks
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Study on the Wavelength-Dependent Temporal Waveform Characteristics of a High-Pressure CO2 Master Oscillator Power Amplifier System

open access: yesPhotonics
This study systematically investigates the temporal characteristics of a high-pressure CO2 master oscillator power amplifier (MOPA) system under tunable spectral lines.
Zefan Huang   +8 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Wavelength shift of atomic spectral lines

open access: yes, 2003
One-dimension wavelength shift of atomic spectral lines in 0-800 nm spectral range was observed, and the relationships between temperature, humidity, pressure, and the magnitudes of wavelength shift of the atomic spectral lines were found, which were ...
刘克玲
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Spectral optical monitoring of a double-peaked emission line AGN Arp 102B: Variability of spectral lines and continuum⋆ [PDF]

open access: yes, 2013
Context. We present results of long-term (1987–2010) optical spectral monitoring of the broad-line radio galaxy Arp 102B, a prototype of an active galactic nucleus with double-peaked broad emission lines that are commonly assumed to be emitted from an ...
Luis Carrasco Bazúa   +4 more
core  

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