Results 51 to 60 of about 442,060 (253)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
OPTIMIZATION OF NONLINEAR STOCHASTIC SYSTEMS IN THE SPECTRAL CHARACTERISTICS OF CONTROLS
Научный вестник МГТУ ГА, 2017 The author presents the spectral method of determining relatively optimal control in case of incomplete infor- mation about the state vector for multidimensional nonlinear continuous stochastic systems, which are governed by Itô’s stochastic differential
K. A. Rybakov
doaj
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2015 The inverse problem of finding the initial distribution has been studied on the basis of formulas for the solution of the first initial-boundary value problem for the inhomogeneous two-dimentional heat equation. The uniqueness of the solution of the direct
Artur R Zaynullov
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Solution of Fractional Optimal Control Problems with Noise Function Using the Bernstein Functions [PDF]
Control and Optimization in Applied Mathematics, 2019 This paper presents a numerical solution of a class of fractional optimal control problems (FOCPs) in a bounded domain having a noise function by the spectral Ritz method.
Ali Nemati +2 more
doaj +1 more source
Applied Sciences, 2023 In order to design a low-noise water-filled pipeline system, it is necessary to obtain knowledge of the dispersion characteristics of axial propagation modes in different water-filled elastic tubes.
Zirong Gao +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2013 The first boundary value problem was considered for the second order loaded differential equation of mixed elliptic-hyperbolic type in a rectangular region.
Olga Anatolievna Arhipova
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source