Results 121 to 130 of about 42,713 (266)
Journal of Medical Imaging and Radiation Oncology, EarlyView.ABSTRACT Introduction Accurate staging is essential in anal cancer to guide therapy and prognostication. While MRI remains the modality of choice for local staging, its limitations in assessing nodal and distant metastases have prompted evaluation of FDG PET/CT as an adjunct.
Hugo C. Temperley +12 more
wiley +1 more source
Asia Pacific Viewpoint, EarlyView.ABSTRACT This study investigates how Nishi‐Kawaguchi Chinatown, a Chinese ethnic enclave in suburban Tokyo, functions as a ‘socioeconomic emergency elevator’ for Chinese migrants. The enclave serves a dual purpose: offering refuge from social exclusion and facilitating upward socioeconomic mobility.
Hiroya Takamatsu
wiley +1 more source
Cancer Science, EarlyView.Using integrated spatial pathomics and transcriptomics, we show that neoadjuvant therapy (NAT) in pancreatic ductal adenocarcinoma (PDAC) induces substantial tumor microenvironment remodeling that is not captured by tumor regression grading (TRG) alone.
Xiaofei Zhang +16 more
wiley +1 more source
Cell Proliferation, EarlyView.Nanosilicates triggered MAP4‐dependent microtubule remodelling via the ROS/MAPK pathway, shifting microtubules into a dynamic active state, which subsequently promoted activation of the STAT3 pathway, ultimately facilitating periodontal angiogenesis.
Lingling Shang, Yuhan Hu, Shaohua Ge
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller +2 more
wiley +1 more source
Hepatology Research, EarlyView.ABSTRACT Background Conversion therapy, which seeks to achieve curative treatment following systemic therapy, is increasingly acknowledged in the management of unresectable hepatocellular carcinoma (HCC). However, validated criteria for predicting eligibility for conversion remain unclear. We investigated the utility of the recently proposed borderline
Yasuto Takeuchi +20 more
wiley +1 more source
Journal of Child Psychology and Psychiatry, EarlyView.Eating disorders are prevalent and profoundly debilitating psychiatric conditions with multifactorial etiology that frequently manifest during adolescence. This developmental stage is characterized by significant neurostructural and neurofunctional change, which may create a context conducive to the emergence of eating pathology.
Kelsey Hagan +2 more
wiley +1 more source
A deep learning–clinical nomogram hybrid for predicting sentinel lymph node metastasis in melanoma
Journal of the European Academy of Dermatology and Venereology, EarlyView.We developed MISSLE, a deep learning–clinical nomogram hybrid model, to predict sentinel lymph node metastasis in invasive cutaneous melanoma with a high area under the receiver operating characteristic curve of 0.950 on the test set. MISSLE identifies key histopathological features and integrates AI for improved clinical decision‐making.
Minh‐Khang Le +8 more
wiley +1 more source
Deciphering the biosynthetic pathways of lichen acids
New Phytologist, EarlyView.Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim +11 more
wiley +1 more source