Results 121 to 130 of about 42,606 (261)

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Near‐resonant excitation of the Adriatic barotropic modes: The seiche events of December 2019

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
This study examines severe flooding in the northern Adriatic Sea in December 2019, which existing forecasting systems failed to predict. Analysis of wind and sea‐level data, alongside reanalysis datasets and a high‐resolution hydrodynamic model, revealed a wind‐induced resonance mechanism.
Marco Bajo   +3 more
wiley   +1 more source

Climate‐Driven Mangrove Dieback and Recovery: A Case Study in Albert and Leichhardt Rivers, Australia

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Cycles of dieback and recovery drove mangrove forest dynamics at the Albert and Leichhardt Rivers (Gulf of Carpentaria, Queensland, Australia) over 36 years (1987–2023). Landward margins were the most affected by reduced tidal inundation when the alignment of low lunar declination suppressed tidal range and extreme El Niño phases lowered mean sea level.
Rogerio Victor S. Gonçalves   +4 more
wiley   +1 more source

The Pier Luigi Nervi's concrete structure of Palazzetto dello Sport: Modeling and dynamic characterization

open access: yesStructural Concrete, EarlyView.
Abstract This paper presents a numerical and experimental study aimed at the modeling and dynamic characterization of the reinforced concrete structure of the Palazzetto dello Sport in Rome, designed and by Pier Luigi Nervi with Annibale Vitellozzi, and built by Nervi & Bartoli contractors in 1956‐57.
Jacopo Ciambella   +2 more
wiley   +1 more source

Cenozoic Tectonics Ignite Mitochondrial Codon Innovations Propelling Canid Body Size Evolution and Transcontinental Radiations

open access: yesIntegrative Zoology, EarlyView.
We decode mitochondrial genomes across all extant canids, revealing lineage‐specific codon optimization driven by altitude, predation, and body size. A tripartite framework integrates geological events, metabolic constraints, and adaptive radiation to explain carnivore evolution.
Xiaoyang Wu   +8 more
wiley   +1 more source

Guideline of guidelines: pelvic lymph node dissection at time of radical prostatectomy

open access: yesBJU International, EarlyView.
Objective To provide a comprehensive review, analysis and critique of guidelines from various oncological and urological organisations regarding the use pelvic lymph node dissection (PLND) in men undergoing radical prostatectomy (RP) for primary treatment of prostate cancer (PCa).
Jonathon Carll   +8 more
wiley   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

open access: yesCell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang   +11 more
wiley   +1 more source

Multiaxial Fatigue Behavior of AA6016 and AA6016 to DX54D SPR Joints: Fracture Mechanisms and Data‐Driven Rupp's Model

open access: yesFatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT The fatigue and fracture behavior of self‐piercing rivet (SPR) joints between AA6016 aluminum sheets (1–2 mm) and DX54D steel (0.95 mm) was studied under 90°, 45°, and 0° multiaxial loading. Pure shear (90°) loading produced the highest fatigue strength, whereas multiaxial (45°) loading resulted in reduced performance, with pure tension (0 ...
Alan Woo   +5 more
wiley   +1 more source

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

open access: yesHistopathology, EarlyView.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak   +22 more
wiley   +1 more source

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