Results 31 to 40 of about 1,153,173 (275)

Gamma spectrometry analysis and health risk assessment of edible liquids [PDF]

Kragujevac Journal of Science, 2023
Examination of radioactivity in edible liquids is very important because large amounts are taken into the body during the day. This scientific paper presents a comprehensive study on the gamma spectrometry analysis and health risk assessment of edible ...
Cimbaljević Željko M., Živković Milena P., Milošević Marko M., Krstić Dragana Ž., Miladinović Tatjana B., Marković Vladimir M., Stevanović Nenad D.   +6 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Advances in Materials Science and Engineering Assessment of Gamma Radiation Hazards Related to Geologic Materials: Comparison of Results by Field Gamma Spectrometry and Laboratory Methods

Advances in Materials Science and Engineering, 2018
Geologic materials are a potential source of external gamma radiation in buildings due to the presence of radioisotopes (40K and isotopes from U and Th decay families).
Miguel Couto, Jorge Sanjurjo-Sánchez, Carlos Alves   +2 more
doaj   +1 more source

REFERENCE SURFACE FOR IN SITU GAMMA SPECTROMETRY

Radiation Protection Dosimetry, 2019
Abstract Chemical laboratories of the Fire Rescue Service of the Czech Republic are part of the radiation monitoring network and participate in the radiation situation monitoring in the Czech Republic. Measurements in situ are crucial for monitoring the radiation situation in emergencies associated with the deposition of radioactive ...
Tomáš, Kroupa, Michal, Setnička, Alena, Čtvrtečková, René, Marek   +3 more
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

EMERGENCY PREPAREDNESS OF GAMMA SPECTROMETRY LABORATORIES

Radiation Protection Dosimetry, 2019
Abstract Currently, the territorial Radiation Monitoring Network (RMN) of the Czech Republic consists of seven laboratories equipped with gamma spectrometry High Purity Germanium (HPGe) detectors. From 2007 to 2018, five emergency exercises were carried out to test the sample throughput of these facilities and their staff.
Michal, Sloboda, Helena, Malá, Petr, Rulík, Věra, Bečková   +3 more
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A generalized mathematical model for efficiency calibration of gamma detectors: Application to practical cases [PDF]

Nuclear Technology and Radiation Protection, 2019
Efficiency calibration, i. e. determination of detection efficiency, εp, is a crucial issue in gamma spectrometry (quantification of gamma spectroscopic measurements) with semiconductor and scintillation detectors. Comparing three possible ways to
Mihaljević Nikola N., Jovanović Slobodan I., Dlabac Aleksandar D.   +2 more
doaj   +1 more source