Results 281 to 290 of about 544,006 (376)

The Site of Protonation Affects the Dissociation of Protonated α- and β-Pinene Ions. [PDF]

Rapid Commun Mass Spectrom
Buenger EW, Mayer PM.
europepmc   +1 more source

Mono‐Ethyl‐Phosphonates: Functional Group Masking Strategy to Stabilize and Optimize the Pharmacokinetics of Rare Earth Radiochelates

ChemistryEurope, EarlyView.
Prodrug strategies are used to enhance the pharmacokinetics of small molecule drugs. Here, this approach to rare earth coordination complexes is adopted with applications as diagnostic and therapeutic radiopharmaceuticals: a mono‐ethyl‐phosphonate polyazamacrocyclic chelator for 44Sc and 177Lu reduces blood and bone uptake.
Jennifer N. Whetter, Axia Marlin, Edith K. Amason, Eduardo Aluicio‐Sarduy, Angus J. Koller, Phuong Nguyen Tran, Kaelyn V. Becker, Jonathan W. Engle, Eszter Boros   +8 more
wiley   +1 more source

Optimisation of Heated Electrospray Ionisation Parameters to Minimise In-Source Generated Impurities in the Analysis of Oligonucleotide Therapeutics. [PDF]

Rapid Commun Mass Spectrom
Glenister MA, Mistarz U, Cook K, Stephenson JL, Dickman MJ.   +4 more
europepmc   +1 more source

Tailoring Ultrashort Inter‐Fullerene Spacing in a Continuous Fullerene Stacking Array to Enhance Electron Transport for Boosting Solar‐Driven Hydrogen Production

Carbon Energy, EarlyView.
The photocatalyst ImC60‐ZnTPP has a unique ultrashort inter‐fullerene spacing in a continuous fullerene stacking array for enhancing electron transport, demonstrating a hydrogen evolution rate of 80.95 mmol·g−1·h−1. This work not only provides a strategy to develop a high‐performance photocatalyst but also provides an avenue for advancing organic ...
Yupeng Song, Chong Wang, Ying Jiang, Zihui Hua, Tianyang Dong, Ruizhi Liu, Rui Wen, Jiechao Ge, Chunru Wang, Bo Wu   +9 more
wiley   +1 more source

A Fast-Pass, Desorption Electrospray Ionization Mass Spectrometry Strategy for Untargeted Metabolic Phenotyping. [PDF]

J Am Soc Mass Spectrom
Shepard HS, May JC, Zuniga BE, Abraham JP, Pfleger BF, Young JD, McLean JA.   +6 more
europepmc   +1 more source

Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9

Chemistry – A European Journal, EarlyView.
We present new BRD9‐targeting degraders featuring a chemical warhead and E3 ligase ligand that distinctly differ from the typical chemical units used for BRD9 degradation. Specifically, we identified two VHL‐based PROTACs (2 and 9) based on a [1,2,4]triazolo[4,3‐a]quinoxaline scaffold that effectively and selectively degrade BRD9 and exhibit ...
Martina Pierri, Guglielmo Bove, Erica Gazzillo, Ester Colarusso, Francesca Scala, Giacomo Pepe, Stefania Terracciano, Maria Giovanna Chini, Nicla Simonelli, Ines Bruno, Angela Nebbioso, Pietro Campiglia, Giuseppe Bifulco, Lucia Altucci, Nunzio Del Gaudio, Gianluigi Lauro   +15 more
wiley   +1 more source

Topographic imaging with automatic z-axis correction of Brassica oleracea var. viridis leaves by IR-MALDESI mass spectrometry imaging. [PDF]

Anal Bioanal Chem
Mills Q, Ashbacher SM, Sohn AL, Muddiman DC.   +3 more
europepmc   +1 more source

Perturbation-Modulated Native Mass Spectrometry Excludes a Nonspecific Drug Target Protein Binder Based on Conformation Stability Change. [PDF]

Anal Chem
Tian X, Mueller P, Sosnowski P, Li F, Guan D, Jacquet C, Hopfgartner G.   +6 more
europepmc   +1 more source

Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging (nano-DESI MSI): A Tutorial Review

ACS Measurement Science Au
Mushfeqa Iqfath, Syeda Nazifa Wali, Sara Amer, Emerson Hernly, Julia Laskin   +4 more
doaj   +1 more source

An update on latest regulatory guidelines and analytical methodologies for N-nitrosamine impurities in pharmaceutical products - 2024. [PDF]

Med Gas Res
Manchuri KM, Kuril AK, Shaik MA, Gopireddy VSR, Sultana N.   +4 more
europepmc   +1 more source