Results 291 to 300 of about 544,006 (376)

From Biomarker Discovery to Clinical Applications of Metabolomics in Glioblastoma. [PDF]

open access: yesMetabolites
Šamec N   +4 more
europepmc   +1 more source

Conformational effects in protein electrospray‐ionization mass spectrometry

Mass Spectrometry Reviews, 2015
Electrospray‐ionization mass spectrometry (ESI‐MS) is a key tool of structural biology, complementing the information delivered by conventional biochemical and biophysical methods. Yet, the mechanism behind the conformational effects in protein ESI‐MS is an object of debate.
Paolo Carloni   +6 more
openaire   +5 more sources

Electrospray ionization for mass spectrometry of large biomolecules.

Science, 1989
Electrospray ionization has recently emerged as a powerful technique for producing intact ions in vacuo from large and complex species in solution. To an extent greater than has previously been possible with the more familiar "soft" ionization methods ...
J. Fenn   +4 more
semanticscholar   +1 more source

Electrospray ionization mass spectrometry of ginsenosides

Journal of Mass Spectrometry, 2002
AbstractGinsenosides Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg2 and F11 were studied systematically by electrospray ionization mass spectrometry in positive‐ and negative‐ion modes with a mobile‐phase additive, ammonium acetate. In general, ion sensitivities for the ginsenosides were greater in the negative‐ion mode, but more structural information on the ...
Chris D. Metcalfe   +3 more
openaire   +3 more sources

Electrospray Ionization Ion Mobility Mass Spectrometry

Critical Reviews in Analytical Chemistry, 2021
Electrospray ionization ion mobility mass spectrometry (ESI-IMS-MS) is a rapidly progressing analytical technique for the examination of complex compounds in the gas phase. ESI-IMS-MS separates isomers, provides structural information, and quantitatively identifies peptides, lipids, carbohydrates, polymers, and metabolites in biological samples.
Katie M. Kohoutek   +1 more
openaire   +2 more sources

Secondary electrospray ionization ion mobility spectrometry/mass spectrometry of illicit drugs.

Analytical Chemistry, 2000
A secondary electrospray ionization (SESI) method was developed as a nonradioactive ionization source for ion mobility spectrometry (IMS). This SESI method relied on the gas-phase interaction between charged particles created by electrospray ionization ...
Ching Wu, William F. Siems, H. H. Hill
semanticscholar   +1 more source

Electrospray Ionization Mass Spectrometry of Oligonucleotides

Current Protocols in Nucleic Acid Chemistry, 2008
AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Colette M. Castleberry   +2 more
openaire   +3 more sources

Electrospray ionization mass spectrometry of metalloporphyrins

Journal of Mass Spectrometry, 1998
The magnesium, nickel, copper, zinc and vanadium metalloporphyrins from octaethylporphyrin, etioporphyrin I and tetraphenylporphyrin were characterized using electrospray ionization mass spectrometry (ESI-MS). The ion abundance of each of the porphyrins present in binary mixtures was monitored as a function of the porphyrin concentration and is ...
Patrick A. Limbach, Victor E. Vandell
openaire   +3 more sources

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