Results 81 to 90 of about 1,589,502 (297)
Scientific Journal of Gdynia Maritime University, 2017 During exploitation, the engine oil undergoes the irreversible aging process that is – degradation. The speed of this process is affected by many factors such as high temperature, pressure, power output, oxygen from the air, mechanical shear forces, type,
M. Malinowska
doaj
Gamma spectrometric measurements of radon daughter 214Bi in surface waters [PDF]
Geofísica Internacional, 2002 Gamma spectrometric measurements of 214Bi and 208Tl have been performed in water and bottom sediments of the Odra river, Poland, and some of its tributaries. Obtained results indicate that radon flux from the bottom sediment is significantly greater than
A. T. Solecki
doaj
Sunflower Plants as Bioindicators of Environmental Pollution with Lead (II) Ions
Sensors, 2009 In this study, the influence of lead (II) ions on sunflower growth and biochemistry was investigated from various points of view. Sunflower plants were treated with 0, 10, 50, 100 and/or 500 µM Pb-EDTA for eight days. We observed alterations in growth in
Radka Opatrilova +9 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Accumulation of glycosidically bound compounds in Fragaria x ananassa cv. Elsanta fruits at various developmental stages [PDF]
Biotechnologie, Agronomie, Société et Environnement, 1999 Isolation of glycosidically bound compounds of Fragaria x ananassa cv. Elsanta was performed by Amberlite XAD-2 adsorption followed by methanol elution.
Groyne J., Lognay G., Marlier M.
doaj
Nature Methods, 2017 Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography–mass spectrometry (GC-MS) metabolome database to match unknowns with ...
Zijuan Lai +13 more
semanticscholar +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source