Results 81 to 90 of about 1,232,276 (317)
Automated, parallel mass spectrometry imaging and structural identification of lipids [PDF]
, 2018 We report a method that enables automated data-dependent acquisition of lipid tandem mass spectrometry data in parallel with a high-resolution mass spectrometry imaging experiment.
Mark W. Jervelund +20 more
core +1 more source
NEW METHOD OF DRUGS DELIVERY TO THE OCULAR SURFACE
Сибирский научный медицинский журнал, 2019 The effectiveness of topical application of various drugs in ophthalmology is no more than 3 % due to the presence of anatomical and physiological barriers.
T. N. Safonova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article summarizes the basic principles of mass spectrometry instrumentation with special emphasis in sample introduction methods, ionization techniques and mass analyzers used in ...
Teixidor Casamitjana, Pilar +6 more
core
Expanding the mass range for UVPD-based native top-down mass spectrometry
, 2019 Native top-down mass spectrometry is emerging as a methodology that can be used to structurally investigate protein assemblies. To extend the possibilities of native top-down mass spectrometry to larger and more heterogeneous biomolecular assemblies ...
Fagerlund, Robert D. +12 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2017 This thesis illustrates the current standing of mass spectrometry (MS) in molecular and structural biology. The primary aim of the herein described research is to facilitate protein characterization by combining mass spectrometric methods among each ...
Lössl, P. +2 more
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Influence of Chemical Composition on Cobalt-Based Alloys
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials ScienceCobalt-based alloys contain up to 50% cobalt, which means that they provide the material with increased abrasion resistance at high temperatures. Cobalt is similar to nickel because it is a hard material that is very resistant to wear and corrosion ...
Mirabela Georgiana MINCIUNA +1 more
doaj +1 more source
Investigations of Latvian Illite/Kaolinite Clays Irradiated Under Action of Accelerated Electrons
Medžiagotyra, 2019 Natural clay is a perspective material for application as sorbents for wastewater treatment as well as for sorption of radionuclides, where the properties of the clays can be changed under influence of ionizing radiation.
Dāvis CONKA +7 more
doaj +1 more source