Results 51 to 60 of about 855,477 (278)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Spectral Characteristics of Cholesterol in Blood by Using Simple Semiconductor Laser [PDF]

open access: yesEngineering and Technology Journal, 2010
In the present work, the possibility of using laser to analyze and find the concentration of total cholesterol (TC) in serum. Semiconductor laser diode of 5mW maximum power, 532nm wavelength and 4nm bandwidth is used to accomplish assay measurements. The
Abdul Rahman Rashid Mohammed
doaj   +1 more source

High Resolution Spectrometry of Leaf and Canopy Chemistry for Biochemical Cycling [PDF]

open access: yes, 1985
High-resolution laboratory spectrophotometer and Airborne Imaging Spectrometer (AIS) data were used to analyze forest leaf and canopy chemistry. Fundamental stretching frequencies of organic bonds in the visible, near infrared and short-wave infrared are
Acevedo, W.   +3 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Apical sealing ability of two novel root canal sealers: An ex-vivo study

open access: yesJournal of International Clinical Dental Research Organization, 2013
Objective: The objective was to compare the sealing ability of two root canal sealers viz.: Hybrid Root SEAL (Sun Medical, Tokyo, Japan) and iRoot SP (Innovative BioCeramix Inc., Vancouver, Canada).
Priyanka Setia   +3 more
doaj   +1 more source

Design, characterization, and fabrication of solar-retroreflective cool-wall materials [PDF]

open access: yes, 2020
Raising urban albedo increases the fraction of incident sunlight returned to outer space, cooling cities and their buildings. We evaluated the angular distribution of solar radiation incident on exterior walls in 17 U S.
Berdahl, P   +5 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Colour analysis of degraded parchment [PDF]

open access: yes, 2013
Multispectral imaging was employed to collect data on the degradation of an 18th century parchment by a series of physical and chemical treatments. Each sample was photographed before and after treatment by a monochrome digital camera with 21 narrow-band
Giacometti, A   +4 more
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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