Results 51 to 60 of about 526,297 (305)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Apical sealing ability of two novel root canal sealers: An ex-vivo study

Journal of International Clinical Dental Research Organization, 2013
Objective: The objective was to compare the sealing ability of two root canal sealers viz.: Hybrid Root SEAL (Sun Medical, Tokyo, Japan) and iRoot SP (Innovative BioCeramix Inc., Vancouver, Canada).
Priyanka Setia, Vimal K. Sikri, Renu B. Sroa, Baljeet Sidhu   +3 more
doaj   +1 more source

Spectral Characteristics of Cholesterol in Blood by Using Simple Semiconductor Laser [PDF]

Engineering and Technology Journal, 2010
In the present work, the possibility of using laser to analyze and find the concentration of total cholesterol (TC) in serum. Semiconductor laser diode of 5mW maximum power, 532nm wavelength and 4nm bandwidth is used to accomplish assay measurements. The
Abdul Rahman Rashid Mohammed
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

In Vitro Comparative Study of Antioxidant and Antibacterial Activity of Selected Dietary Plants

Nepal Journal of Biotechnology, 2018
Ethanolic extracts of Garlic (Bulb), Aloe (leaf), Flower bud (buds), Turmeric (rhizomes) and Ginger (rhizomes) were used for relative analysis of antioxidant and antimicrobial activity.
Ashok Kumar, Palvi Sharma, Anupama Mahajan, Zarina Begum   +3 more
doaj   +1 more source

Color stability of a resin composite: Effect of the immersion method and surface treatments

Indian Journal of Dental Research, 2016
Background: In vitro staining methods expose the entire specimen to staining solutions. In a real clinical situation, this is not observed, since one should consider that the bonded surface is not exposed to the oral environment.
L L Miotti, G F Nicoloso, L B Durand, A H Susin, R O Rocha   +4 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Effect of Various External Shading Devices on Windows for Minimum Heat Gain and Adequate Day lighting into Buildings of Hot and Dry Climatic Zone in India

MATEC Web of Conferences, 2018
Glass is the major component of the building envelope to provide visual comfort to inside the buildings. In général clear and bronze glass was used as a main building envelope for both residential and commercial buildings to provide better day lighting ...
Kirankumar Gorantla, Saboor Shaik, Talanki Setty Putta Ranga, Babu Ashok   +3 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source