Results 131 to 140 of about 217,951 (354)

Oral Microalgae‐Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng   +8 more
wiley   +1 more source

Two-micron spectrophotometry of the galaxy NGC 253 [PDF]

open access: yes, 1979
A very strong Brackett-gamma hydrogen emission line, and the 2.3 micron CO stellar absorption feature were measured in NGC 253. The presence and strength of the CO feature indicates that late type giant stars produce most of the 2.2 micron continuum ...
Becklin, E. E.   +3 more
core   +1 more source

The Distance to the Large Magellanic Cloud from the Eclipsing Binary HV2274 [PDF]

open access: yes, 1998
The distance to the Large Magellanic Cloud (LMC) is crucial for the calibration of the Cosmic Distance Scale. We derive a distance to the LMC based on an analysis of ground-based photometry and HST-based spectroscopy and spectrophotometry of the LMC ...
A. Giménez   +10 more
core   +3 more sources

An Anti‐CD147 Antibody−Drug Conjugate Mehozumab‐DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey

open access: yesAdvanced Science, EarlyView.
Antibody‐drug conjugates are among the fastest‐growing drugs in oncology. It combines the potent killing activity of small molecular drugs and the high specific targeting of antibody drugs. Our in vitro and in vivo studies suggest that anti‐CD147 ADC Mehozumab‐DM1 potently inhibits hepatocellular carcinoma, and combining CD147‐ADCs and targeted therapy
Wan Huang   +16 more
wiley   +1 more source

Modular Calcium‐Responsive and CD9‐Targeted Phospholipase System Enhancing Endosomal Escape for DNA Delivery

open access: yesAdvanced Science, EarlyView.
A modular endosomal escape system boosts transfection efficiency of a DNA delivery agent. This system comprises a phospholipase fused to a split‐calbindin domain and a nanobody targeting CD9. In the extracellular space, the phospholipase is tightly bound to protein‐DNA complexes, released within endosomes at low calcium concentrations and recruited to ...
Alexander Klipp   +5 more
wiley   +1 more source

Silica‐gel incorporated carbon paste sensor for the electrocatalytic oxidation of famotidine and its application in biological sample analysis

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Graphical Abstract. Abstract Famotidine (FAM) is an efficacious competitive drug, and a reversible inhibitor of H2‐histaminergic receptor action used to manage acid production in the stomach. Among the elderly population, this drug poses the risk of kidney failure and impaired mental health conditions. Additionally, FAM is an environmental contaminant.
Pramod Ramachandra Vernekar   +4 more
wiley   +1 more source

A 2:2:2 Complex of Vanadium(V) with 4-(2-Thiazolylazo)orcinol and 2,3,5-Triphenyl-2H-Tetrazolium Chloride

open access: yesActa Chimica Slovenica, 2016
The complex formation in the vanadium(V) / 4-(2-thiazolylazo)orcinol (TAO) / 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) liquid-liquid extraction-chromogenic system was studied.
Kiril Blazhev Gavazov   +4 more
doaj   +1 more source

Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy

open access: yesAdvanced Science, EarlyView.
Selenium electrophilic center intelligently responds to different ratio of biological electron donors/receptors in cancer cells and normal cells to achieve highly effective and less toxic chemotherapy. Abstract Designing drugs to intelligently respond to different ratio of biological electron donors/receptors in cancer cells and normal cells is a ...
Xiaoyu Qin   +8 more
wiley   +1 more source

Electrochemically mediated multi‐modal detection strategy‐driven sensor platform to detect and quantify pesticides

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract With the emergence of modern agronomy practices and the use of multiple synthetic pesticide agents to keep control over crop and field throughput, there lies a broad requirement for smart, accessible technologies to track pesticide contaminants in food, water, and other environmental matrices.
Vikram Narayanan Dhamu   +5 more
wiley   +1 more source

Lipid Peroxidation Process in Meat and Meat Products: A Comparison Study of Malondialdehyde Determination between Modified 2-Thiobarbituric Acid Spectrophotometric Method and Reverse-Phase High-Performance Liquid Chromatography

open access: yesMolecules, 2017
The aim of this work was to compare the methods of malondialdehyde detection, as the main secondary product of the lipid peroxidation process, in meat and meat products.
Anna Reitznerová   +6 more
doaj   +1 more source

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