Results 71 to 80 of about 127,521 (247)

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Estimating organic matter acid-base properties and electrical charge by spectrophotometry [PDF]

, 2023
Marawit Tesfa, Rémi Marsac, Aline Dia, Fabrice Mahé, Noémie Janot   +4 more
openalex   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Study of the ascorbic acid accumulation in Thymus L. genus species of Ukraine flora

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
The Thymus L. genus species are extremely widespread in temperate countries and number up to 200 main wild plants, of which up to 50 have been identified in the modern Ukraine flora. Extracts from the official species of the Thymus L.
O. V. Mazulin, Ya. M. Steshenko, L. A. Fukleva, H. V. Mazulin   +3 more
doaj   +1 more source

Determination of Silica in Geological Samples by Silicon-Molybdenum Blue Spectrophotometry Using High-pressure Acid Digestion

Yankuang ceshi, 2019
BACKGROUND Polymerized silicic acid cannot be quantitatively complexed with molybdate in geological sample, therefore the silicon is determined by silicon-molybdenum blue colorimetric spectrophotometry.
DONG Xue-lin, HE Hai-yang, CHU Qin, SONG Zhou   +3 more
doaj   +1 more source

ZIF‐67‐Confined Pd Single‐Atom Catalysts Implanted Into Polydopamine‐Modified Bamboo Microchannels for Robust Continuous‐Flow Hydrogenation

Advanced Science, EarlyView.
The report presents a facile room‐temperature method to stabilize Pd single‐atom catalysts within ZIF‐67 crystals during their formation. Despite an ultralow Pd loading (0.0014 wt%), the catalytic microreactor, featuring atomically dispersed Pd‐N4 sites in ZIF‐67, demonstrates superior robustness and maximized Pd utilization, significantly ...
Sisi Yao, Jiawei Han, Wenjun Zhang, Dengkang Guo, Shenjie Han, Yun Lu, Jingpeng Li   +6 more
wiley   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

Spectrophotometric Analysis of Dental Staining Induced by Different Pulpotomy Materials

Indian Journal of Dental Sciences
Background: Pulpotomy is an endodontic procedure for primary and permanent dentition. Different pulp materials, such as calcium hydroxide and silicate-based materials are used in pulpotomy.
Nour Hanzaz, Ann-Sophie Van Hamme, Clara Descombels, Amir Shayegan   +3 more
doaj   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

Analysis of Unamplified 16s Rrna of Ammonia-Oxidizing Bacteria in Activated Sludge by Spectrophotometry Using Gold Nanoprobes

, 2023
Hisashi Satoh, Meri Nakajima, Reiko Hirano, Yuki Nakaya   +3 more
openalex   +1 more source