Results 81 to 90 of about 1,313,477 (397)

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

FEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

The IACOB project. V. Spectroscopic parameters of the O-type stars in the modern grid of standards for spectral classification [PDF]

, 2018
The IACOB and OWN surveys are two ambitious complementary observational projects which have made available a large multi-epoch spectroscopic database of optical high resolution spectra of Galactic massive O-type stars. As a first step in the study of the
Apellániz, J. Maíz, Barbá, R. H., Castro, N., Garcia, M., Herrero, A., Holgado, G., Negueruela, I., Puls, J., Sabín-Sanjulián, C., Simón-Díaz, S.   +9 more
core   +3 more sources

The 13th Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the SDSS-IV Survey Mapping Nearby Galaxies at Apache Point Observatory [PDF]

, 2016
The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) began observations in 2014 July. It pursues three core programs: the Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2), Mapping Nearby Galaxies at APO (MaNGA), and the ...
S. C. F. D. Albareti, C. Prieto, Andres Almeida, F. Anders, S. Anderson, B. Andrews, A. Aragón-Salamanca, M. Argudo-Fernández, E. Armengaud, E. Aubourg, V. Avila-Reese, C. Badenes, S. Bailey, B. Barbuy, K. Barger, J. Barrera-Ballesteros, Curtis Bartosz, S. Basu, Dominic J Bates, G. Battaglia, Falk Baumgarten, J. Baur, J. Bautista, T. Beers, F. Belfiore, M. Bershady, S. B. D. Lis, J. Bird, D. Bizyaev, G. Blanc, M. Blanton, M. Blomqvist, A. Bolton, J. Borissova, J. Bovy, W. Brandt, J. Brinkmann, J. Brownstein, K. Bundy, É. Burtin, N. Busca, H. Chavez, M. C. Díaz, M. Cappellari, R. Carrera, Yanping Chen, B. Cherinka, Edmond Cheung, C. Chiappini, D. Chojnowski, C. Chuang, Haeun Chung, R. Cirolini, N. Clerc, R. Cohen, J. Comerford, J. Comparat, M. Cousinou, K. Covey, J. Crane, R. Croft, K. Cunha, L. Costa, G. S. Ilha, J. Darling, James W. Davidson, K. Dawson, N. D. Lee, A. Macorra, S. D. Torre, Alice Deconto Machado, T. Delubac, A. Diamond-Stanic, J. Donor, J. J. Downes, N. Drory, Hélion Marie du Mas des Bourboux, Cheng Du, T. Dwelly, G. Ebelke, A. Eigenbrot, D. Eisenstein, Y. Elsworth, E. Emsellem, M. Eracleous, S. Escoffier, M. Evans, J. Falcón-Barroso, Xiaohui Fan, G. Favole, E. Fernández-Alvar, J. Fernández-Trincado, D. Feuillet, S. Fleming, A. Font-Ribera, G. Freischlad, P. Frinchaboy, H. Fu, Yang Gao, D. A. García-Hernández, A. G. Pérez, R. García, R. Garcia-Dias, P. Gaulme, J. Ge, D. Geisler, H. Marín, B. Gillespie, L. Girardi, D. Goddard, Y. G. M. Chew, V. Gonzalez-Perez, K. Grabowski, P. Green, C. Grier, Thomas Grier, Hong Guo, J. Guy, A. Hagen, Matt Hall, P. Harding, R. E. Harley, S. Hasselquist, S. Hawley, C. Hayes, F. Hearty, S. Hekker, H. Toledo, S. Ho, D. Hogg, K. Holley-Bockelmann, J. Holtzman, Parker H. Holzer, Jian Hu, D. Huber, T. Hutchinson, H. Hwang, H. Ibarra-Medel, I. Ivans, K. Ivory, K. Jaehnig, Trey W. Jensen, Jennifer A. Johnson, Amy M. Jones, E. Jullo, T. Kallinger, K. Kinemuchi, D. Kirkby, M. Klaene, J. Kneib, J. Kollmeier, I. Lacerna, R. Lane, D. Lang, Pierre Laurent, D. Law, J. Goff, A. Leauthaud, Cheng Li, Ran Li, Chen Li, Niu Li, Fu-heng Liang, Y. Liang, M. Lima, Lihwai Lin, Lin Lin, Yen-Ting Lin, D. Long, S. Lucatello, N. MacDonald, C. MacLeod, J. Mackereth, S. Mahadevan, M. Maia, R. Maiolino, S. Majewski, O. Malanushenko, N. Mallmann, A. Manchado, C. Maraston, R. Marques-Chaves, Inma Martinez Valpuesta, K. Masters, S. Mathur, I. McGreer, A. Merloni, M. Merrifield, S. Mészáros, A. Meza, A. Miglio, I. Minchev, Karan Molaverdikhani, A. Montero-Dorta, B. Mosser, D. Muna, A. Myers, P. Nair, K. Nandra, M. Ness, J. Newman, R. Nichol, D. Nidever, C. Nitschelm, J. O’Connell, A. Oravetz, N. Padilla, N. Palanque-Delabrouille, K. Pan, J. Parejko, I. Pâris, J. Peacock, S. Peirani, M. Pellejero-Ibáñez, S. Penny, W. Percival, J. Percival, I. Pérez-Fournon, P. Petitjean, M. Pieri, M. Pinsonneault, A. Pisani, F. Prada, A. Prakash, Natalie Price-Jones, M. Raddick, Mubdi Rahman, A. Raichoor, S. Rembold, A. Reyna, J. Rich, H. Richstein, J. Ridl, R. Riffel, R. Riffel, H. Rix, A. Robin, C. Rockosi, Sergio A. Rodríguez-Torres, T. Rodrigues, N. Roe, A. R. Lopes, C. Román-Zúñiga, A. Ross, G. Rossi, J. Ruan, R. Ruggeri, J. Runnoe, Salvador Salazar-Albornoz, M. Salvato, A. Sánchez, S. Sánchez, J. Sánchez-Gallego, B. Santiago, Ricardo Schiavon, J. Schimoia, E. Schlafly, D. Schlegel, D. Schneider, R. Schoenrich, M. Schultheis, A. Schwope, H. Seo, A. Serenelli, B. Sesar, Z. Shao, M. Shetrone, M. Shull, V. S. Aguirre, M. Skrutskie, A. Slosar, Michael P. Smith, V. Smith, J. Sobeck, G. Somers, D. Souto, D. Stark, K. Stassun, M. Steinmetz, D. Stello, T. Bergmann, M. Strauss, A. Streblyanska, G. Stringfellow, G. Suárez, Jing Sun, M. Taghizadeh-Popp, B. Tang, C. Tao, J. Tayar, Mita Tembe, D. Thomas, J. Tinker, R. Tojeiro, C. Tremonti, N. Troup, J. Trump, E. Unda-Sanzana, O. Valenzuela, R. V. D. Bosch, M. Vargas-Magaña, J. Vázquez, S. Villanova, M. Vivek, N. Vogt, D. Wake, R. Walterbos, Yuting Wang, E. Wang, B. Weaver, A. Weijmans, D. Weinberg, K. Westfall, D. Whelan, E. Wilcots, V. Wild, Rob A. Williams, John Wilson, W. M. Wood-Vasey, D. Wylezalek, T. Xiao, R. Yan, Meng Yang, J. E. Ybarra, C. Yéche, F. Yuan, N. Zakamska, O. Zamora, G. Zasowski, Kai Zhang, Cheng Zhao, Gong-Bo Zhao, Zheng Zheng, Zhi-min Zhou, G. Zhu, J. Zinn, H. Zou   +336 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Structure identification of potential compound as selective renal anticancer isolated from Nerium indicum Mill. Leaves

Indonesian Journal of Pharmacy, 2008
Oleandrin is one of cardenolida compound isolated from an active fraction of Nerium indicum Mill leaves. (fam. Apocynaceae), which have cytotoxic effect on several human cancer cells, and also to normal cells in vitro.
Mae S.H. Wahyuningsih, Sofia Mubarika, Mark T. Hamann, Ibnu G. Gandjar, Subagus Wahyuono   +4 more
doaj   +1 more source

Optical Spectroscopy of Distant Red Galaxies

, 2009
We present optical spectroscopic follow-up of a sample of Distant Red Galaxies (DRGs) with K 2.3, in the Hubble Deep Field South, the MS 1054-03 field, and the Chandra Deep Field South. Spectroscopic redshifts were obtained for 15 DRGs. Only 2 out of 15
Franx, Marijn, Illingworth, Garth D., Labbe, Ivo, Rudnick, Gregory, Schreiber, Natascha M. Forster, van Dokkum, Pieter G., Wuyts, Stijn   +6 more
core   +1 more source

THE SDSS-IV EXTENDED BARYON OSCILLATION SPECTROSCOPIC SURVEY: OVERVIEW AND EARLY DATA [PDF]

, 2015
In a six-year program started in 2014 July, the Extended Baryon Oscillation Spectroscopic Survey (eBOSS) will conduct novel cosmological observations using the BOSS spectrograph at Apache Point Observatory.
K. Dawson, J. Kneib, W. Percival, S. Alam, F. D. Albareti, S. Anderson, E. Armengaud, E. Aubourg, S. Bailey, J. Bautista, A. Berlind, M. Bershady, F. Beutler, D. Bizyaev, M. Blanton, M. Blomqvist, A. Bolton, J. Bovy, W. Brandt, J. Brinkmann, J. Brownstein, É. Burtin, N. Busca, Z. Cai, C. Chuang, N. Clerc, J. Comparat, F. Cope, R. Croft, I. Cruz-González, L. Costa, M. Cousinou, J. Darling, A. Macorra, S. D. Torre, T. Delubac, Hélion Marie du Mas des Bourboux, T. Dwelly, A. Ealet, D. Eisenstein, M. Eracleous, S. Escoffier, Xiaohui Fan, A. Finoguenov, A. Font-Ribera, P. Frinchaboy, P. Gaulme, A. Georgakakis, P. Green, Hong Guo, J. Guy, S. Ho, D. Holder, J. Huehnerhoff, T. Hutchinson, Y. Jing, E. Jullo, Vikrant Kamble, K. Kinemuchi, D. Kirkby, F. Kitaura, M. Klaene, R. Laher, D. Lang, Pierre Laurent, J. Goff, Cheng Li, Y. Liang, M. Lima, Q. Lin, Weipeng Lin, Yen-Ting Lin, D. Long, B. Lundgren, N. MacDonald, M. Maia, E. Malanushenko, V. Malanushenko, V. Mariappan, C. McBride, I. McGreer, B. Ménard, A. Merloni, A. Meza, A. Montero-Dorta, D. Muna, A. Myers, K. Nandra, T. Naugle, J. Newman, P. Noterdaeme, P. Nugent, R. Ogando, M. Olmstead, A. Oravetz, D. Oravetz, N. Padmanabhan, N. Palanque-Delabrouille, K. Pan, J. Parejko, I. Pâris, J. Peacock, P. Petitjean, M. Pieri, A. Pisani, F. Prada, A. Prakash, A. Raichoor, B. Reid, J. Rich, J. Ridl, Sergio A. Rodríguez-Torres, A. Rosell, A. Ross, G. Rossi, J. Ruan, M. Salvato, Conor Sayres, D. Schneider, D. Schlegel, U. Seljak, H. Seo, B. Sesar, S. Shandera, Y. Shu, A. Slosar, F. Sobreira, A. Streblyanska, N. Suzuki, C. Tao, Donna Taylor, J. Tinker, R. Tojeiro, M. Vargas-Magaña, Yuting Wang, B. Weaver, D. Weinberg, M. White, W. M. Wood-Vasey, C. Yéche, Zhongxu Zhai, Cheng Zhao, Gong-Bo Zhao, Zheng Zheng, G. Zhu, H. Zou   +145 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

The Maunakea Spectroscopic Explorer

Bulletin of the American Astronomical Society, 2019
White paper identifier ...
Hall, Pat, Balogh, Michael, Barmby, Pauline, Blakeslee, John, Bovy, Jo, Bradley, Colin, Bridges, Terry, Cami, Jan, Chapman, Scott, Chateauneuf, Francois, Cowan, Nick, Cote, Patrick, Damjanov, Ivana, Drout, Maria, Eadie, Gwendoyn, Ellison, Aara, Ferrarese, Laura, Fraser, Wesley, Gaensler, Bryan, Gallagher, Sarah, Haggard, Daryl, Henault-Brunet, Vincent, Herwig, Falk, Hill, Alexis, Hlavacek-Larrondo, Julie, Hudson, Mike, Johnson, Matt, Khatu, Viraja, Laporte, Chervin, McConnachie, Alan, McNamara, Brian, Mohammad, Faizan, Muzzin, Adam, Neilson, Hilding, Nemec, James, O'dea, Christopher, Parker, Laura, Patton, David, Percival, Will, Rogerson, Jesse, Ruan, John J., Sakara, Charli, Sawicki, Marcin, Simons, Doug, Sivakoff, Greg, Szeto, Kei, Tesfamariam, Solomon, Thanjavur, Karun, Thibeault, Simon, Thomas, Guillaume, Van Waerbeke, Ludovic, Venn, Kim, Webb, Tracy, Willis, Jon, Woo, Joanna   +54 more
openaire   +4 more sources