Results 111 to 120 of about 3,195,954 (330)

Kinetic selectivity in metal-organic framework chemical sensors

open access: yesNature Communications
Selective detection of specific volatile organic compounds (VOCs) is crucial for health, safety, and environmental applications, but current sensors suffer from poor selectivity and struggle to measure specific VOCs in the presence of interfering ...
Aleksander Matavž   +6 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Structural and time-domain peculiarities of the fluorescence excitation spectra of single Mg-TAP in a polymer at low temperatures

open access: yesEPJ Web of Conferences, 2018
The results of low-temperature measurements of spectral trails (temporal evolutions of individual fluorescence excitation spectra) of single molecules Mg-tetraazaporphyrin embedded in polyisobutylene are presented.
Savostianov Aleksandr   +6 more
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Hadron Spectroscopy at CLEO

open access: yes, 2010
New measurements of the masses and decay branching fractions of charmonium and bottomonium states using the data collected by the CLEO detector are presented.
Tomaradze, Amiran
core   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Seesaw Spectroscopy at Colliders [PDF]

open access: yes, 2011
A low-scale neutrino seesaw may be probed or even reconstructed at colliders provided that supersymmetry is at the weak scale and the LSP is a sterile sneutrino. Because the neutrino Yukawa couplings are small, the NLSP is typically long-lived and thus a
Cheung, Clifford   +2 more
core   +1 more source

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