Results 91 to 100 of about 1,220,984 (295)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Linear and nonlinear abstract differential equations of high order

open access: yesOpen Mathematics, 2015
The nonlocal boundary value problems for linear and nonlinear degenerate abstract differential equations of arbitrary order are studied. The equations have the variable coefficients and small parameters in principal part.
Shakhmurov Veli B.
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Topics on the spectral properties of degenerate non-self-adjoint differential operators

open access: yesJournal of Inequalities and Applications, 2016
Let ( P u ) ( t ) = − d d t ( ω 2 ( t ) q ( t ) d u ( t ) d t ) $( Pu ) ( t ) =- \frac{d}{dt} ( \omega^{2} ( t ) q ( t ) \frac{du ( t )}{dt} )$ be a degenerate non-self-adjoint operator defined on the space H ℓ = L 2 ( 0 , 1 ) ℓ $H_{\ell} = L^{2} (0,1)^{\
Ali Sameripour, Yousef Yadollahi
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Spectral properties of fractional differentiation operators

open access: yesElectronic Journal of Differential Equations, 2018
We consider the fractional differentiation operators in a variety of senses. We show that the strong accretive property is the common property of fractional differentiation operators.
Maksim V. Kukushkin
doaj  

The spectrum of α-resolvable block designs with block size 3

open access: yesDiscrete Mathematics, 1991
A balanced incomplete block design \(D(v,k,\lambda)\) is called \(\alpha\)- resolvable if its blocks can be partitioned into classes such that each point of the design lies in exactly \(\alpha\) blocks of each class. Necessary conditions for such a partitioning to exist include (i) \(bk=vr\); (ii) \(\lambda (v-1)=r(k-1)\); (iii) \(k\mid \alpha v\); (iv)
Jungnickel, Dieter   +2 more
openaire   +1 more source

Norm-resolvent convergence in perforated domains

open access: yes, 2018
For several different boundary conditions (Dirichlet, Neumann, Robin), we prove norm-resolvent convergence for the operator −Δ in the perforated domain Ω∖⋃i∈2εZdBaε(i), aε≪ε, to the limit operator −Δ+μι on L2(Ω), where μι∈Cis a constant depending on the ...
Rösler, Frank   +2 more
core   +1 more source

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