Results 91 to 100 of about 1,220,984 (295)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Linear and nonlinear abstract differential equations of high order
The nonlocal boundary value problems for linear and nonlinear degenerate abstract differential equations of arbitrary order are studied. The equations have the variable coefficients and small parameters in principal part.
Shakhmurov Veli B.
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Topics on the spectral properties of degenerate non-self-adjoint differential operators
Let ( P u ) ( t ) = − d d t ( ω 2 ( t ) q ( t ) d u ( t ) d t ) $( Pu ) ( t ) =- \frac{d}{dt} ( \omega^{2} ( t ) q ( t ) \frac{du ( t )}{dt} )$ be a degenerate non-self-adjoint operator defined on the space H ℓ = L 2 ( 0 , 1 ) ℓ $H_{\ell} = L^{2} (0,1)^{\
Ali Sameripour, Yousef Yadollahi
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Spectral properties of fractional differentiation operators
We consider the fractional differentiation operators in a variety of senses. We show that the strong accretive property is the common property of fractional differentiation operators.
Maksim V. Kukushkin
doaj
The spectrum of α-resolvable block designs with block size 3
A balanced incomplete block design \(D(v,k,\lambda)\) is called \(\alpha\)- resolvable if its blocks can be partitioned into classes such that each point of the design lies in exactly \(\alpha\) blocks of each class. Necessary conditions for such a partitioning to exist include (i) \(bk=vr\); (ii) \(\lambda (v-1)=r(k-1)\); (iii) \(k\mid \alpha v\); (iv)
Jungnickel, Dieter +2 more
openaire +1 more source
Norm-resolvent convergence in perforated domains
For several different boundary conditions (Dirichlet, Neumann, Robin), we prove norm-resolvent convergence for the operator −Δ in the perforated domain Ω∖⋃i∈2εZdBaε(i), aε≪ε, to the limit operator −Δ+μι on L2(Ω), where μι∈Cis a constant depending on the ...
Rösler, Frank +2 more
core +1 more source

