Results 101 to 110 of about 3,788,707 (345)

The Changing Epidemiology of Autism Spectrum Disorders.

open access: yesAnnual Review of Public Health, 2017
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with lifelong impacts. Genetic and environmental factors contribute to ASD etiology, which remains incompletely understood.
K. Lyall   +14 more
semanticscholar   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

An Magnetic Resonance Imaging Case Study: The Anatomic Palate Restoration Concept Utilizing Buccal Flaps in a Primary Palatoplasty

open access: yesPlastic and Reconstructive Surgery, Global Open, 2020
Samuel A. Mann, BS   +3 more
doaj   +1 more source

Cone-beam computed tomography-guided online adaptive radiotherapy is feasible for prostate cancer patients

open access: yesPhysics and Imaging in Radiation Oncology, 2022
Background and purpose: Studies have shown the potential of cone-beam computed tomography (CBCT)-guided online adaptive radiotherapy (oART) for prostate cancer patients in a simulation environment. The aim of this study was to evaluate the feasibility of
Lisanne G.M. Zwart   +7 more
doaj  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

On the Relation Between S-Spectrum and Right Spectrum

open access: yesComplex Analysis and Operator Theory
Abstract We use the $$\mathbb {R}$$ R -linearity of $$I\lambda -T$$ I λ - T
Carvalho, LuÍs   +3 more
openaire   +2 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

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