Results 41 to 50 of about 5,900,600 (309)

Cone-beam computed tomography-guided online adaptive radiotherapy is feasible for prostate cancer patients

open access: yesPhysics and Imaging in Radiation Oncology, 2022
Background and purpose: Studies have shown the potential of cone-beam computed tomography (CBCT)-guided online adaptive radiotherapy (oART) for prostate cancer patients in a simulation environment. The aim of this study was to evaluate the feasibility of
Lisanne G.M. Zwart   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Purity in Seclusion: Exploring the Anchoritic Lifestyle through an Archaeological Lens [PDF]

open access: yes, 2013
This paper uses both archaeological and ethno-historical data to cross-examine theoretical explanations for understanding the anchoritic lifestyle, which are grounded in gender and feminist theory, sexuality and queer theory, as well as theories of ...
Stewart, Monica
core   +2 more sources

The effects of prehabilitation versus usual care to reduce postoperative complications in high-risk patients with colorectal cancer or dysplasia scheduled for elective colorectal resection: study protocol of a randomized controlled trial

open access: yesBMC Gastroenterology, 2018
Background Of all older patients that opt for elective colorectal surgery, approximately one-third has one or more postoperative complications, particularly those patients with a low cardiorespiratory fitness (ventilatory anaerobic threshold (VAT)
Annefleur E. M. Berkel   +12 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Geoglyphs of the Atacama Desert: A Bond of Landscape and Mobility [PDF]

open access: yes, 2012
In the northern-most area of Chile, stretching six hundred miles down the coast of South America and expanding more than forty thousand square miles into Bolivia, Peru and Argentina lies the Atacama Desert.
Labash, Marika
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Approaches to Sensory Landscape Archaeology [PDF]

open access: yes, 2012
As the medium through which humans interact with the physical world, senses are crucial to explore when trying to understand the beings that embody them.
Faycurry, Jessica
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A Completely Endovascular Solution for Transcatheter Aortic Valve Implantation Embolisation and Inversion into the Aortic ArchWhat this paper adds

open access: yesEJVES Vascular Forum, 2021
Introduction: Transcatheter aortic valve implantation (TAVI) has evolved into the preferred alternative to surgical valve replacement for severe aortic valve stenosis with high surgical risk.
Steven J.G. Leeuwerke   +3 more
doaj   +1 more source

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