Results 61 to 70 of about 7,764,522 (352)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Immune Response, Inflammation, and the Clinical Spectrum of COVID-19

open access: yesFrontiers in Immunology, 2020
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly extended to become a global sanitary and economic emergency. Its etiological agent is the coronavirus SARS-CoV-2.
L. Garcia
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Twins in Mesoamerica as a Symbol of Contrasting Duality [PDF]

open access: yes, 2015
In cultures across the Mesoamerican subcontinent, there are examples in the archaeological and ethnographic record of myths concerned with twins and sibling pairs (Minneci, 1999).
Rideout, Benjamin
core   +2 more sources

DFT-Calculated IR Spectrum Amide I, II, and III Band Contributions of N-Methylacetamide Fine Components

open access: yesACS Omega, 2020
The infrared spectrum (IR) characteristic peaks of amide I, amide II, and amide III bands are marked as amide or peptide characteristic peaks. Through the nuclear magnetic resonance study, N-methylacetamide has been determined to have six fine components,
Yan Ji   +8 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Ventricular Septal Rupture in 2 Patients Presenting Late after Myocardial Infarction during the COVID-19 Pandemic

open access: yesJACC: Case Reports, 2020
Ventricular septal rupture (VSR) following myocardial infarction is rare in the reperfusion era. The decrease in patients presenting with myocardial infarction during the coronavirus-2019 (COVID-19) pandemic could result in more frequent VSR. This report
Malav Parikh, MD   +4 more
doaj   +1 more source

Brain‐responsive corticothalamic stimulation in the pulvinar nucleus for the treatment of regional neocortical epilepsy: A case series

open access: yesEpilepsia Open, 2021
Drug‐resistant focal epilepsy with regional neocortical seizure onsets originating from the posterior quadrant can be particularly difficult to treat with resective surgery due to the overlap with eloquent cortex.
David Burdette   +3 more
doaj   +1 more source

Presenting Pompeii: Reconciling Relationships between Configuration and Conservation [PDF]

open access: yes, 2013
Mark Twain’s idealized testimonial in his travelogue Innocents Abroad is not a revolutionary phenomenon. Pompeii has long been considered a city with breathtaking preservation, but the extent of preservation has been a recent source of controversy.
Sheldon, Karilyn
core   +2 more sources

Continuous spectrum, point spectrum and residual spectrum of operator matrices

open access: yesLinear Algebra and its Applications, 2010
Let \(M_C\) denote a \(2\times 2\) upper triangular operator matrix of the form \(M_C=\left(\begin{smallmatrix} A&C\\0&B\end{smallmatrix}\right)\), which is acting on the sum of Banach spaces \(X\oplus Y\) or Hilbert spaces \(H\oplus K\). The authors of this paper characterize the sets \(\bigcap_{C\in B(Y,X)} \sigma_c(M_C)\), \(\bigcap_{C\in B(K,H ...
Zhang, Shifang   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy