Results 51 to 60 of about 24,337,042 (308)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Raman optical activity demonstrates poly(L-proline) II helix in the N-terminal region of the ovine prion protein: Implications for function and misfunction [PDF]

, 2004
The aqueous solution structure of the full-length recombinant ovine prion protein PrP25-233, together with that of the N-terminal truncated version PrP94-233, have been studied using vibrational Raman optical activity (ROA) and ultraviolet circular ...
Rhie, A G O, Nielsen, Kurt, Blanch, EW, Rhie, AGO, Gill, AC, Hope, James, Hecht, L, Gill, Andrew C., Gill, A C, Blanch, E W, Barron, Laurence D., Barron, L D, Nielsen, K, Hope, J, Hecht, Lutz, Barron, LD, Blanch, Ewan W., Rhie, Alexandre G. O., Rhie, Alexandre G O   +18 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Raman analysis of synthetic eritadenine

, 2008
Eritadenine, 2(R),3(R)-dihydroxy-4-(9-adenyl)-butyric acid, is a cholesterol-reducing compound naturally occurring in the shitake mushroom (Lentinus edodes). To identify the unknown Raman spectrum of this compound, pure synthetic eritadenine was examined
Berglund, Kris,, Kris Arvid Berglund, Ramser, Kerstin,, Rova, Ulrika, Josefine Enman, Kerstin Ramser, Enman, Josefine,, Ulrika Rova   +7 more
core   +1 more source

In vivo micro-Raman spectroscopy from an arbitrary-shaped region of interest under simultaneous reflectance confocal imaging guidance

APL Photonics
Confocal Raman spectroscopy (CRS) has been widely used for noninvasive biochemical analysis of biological tissue in vivo. Currently, reflectance confocal microscopy (RCM) has been integrated with CRS as visual guidance for a square-/rectangular-shaped ...
Zhenguo Wu, Liwei Jiang, Jianhua Zhao, Harvey Lui, Haishan Zeng   +4 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Collaborative Penalized Least Squares for Background Correction of Multiple Raman Spectra

Journal of Analytical Methods in Chemistry, 2018
Although Raman spectroscopy has been widely used as a noninvasive analytical tool in various applications, backgrounds in Raman spectra impair its performance in quantitative analysis.
Long Chen, Yingwen Wu, Tianjun Li, Zhuo Chen   +3 more
doaj   +1 more source

Analysis of the torsional Raman spectrum of a pyramidal molecule, dimethylamine

Chemical Physics, 1993
Abstract Overtone Raman spectra of dimethylamine (DMA) are analyzed yielding accurate torsional potential parameters. Neglecting the inversion motion of the amino-hydrogen in DMA the group G 18 is the proper molecular symmetry group to analyze the measured torsional Raman spectrum.
Consalvo, D., Bladel, J.W.I. van, Engeln, R., Reuss, J.   +3 more
openaire   +2 more sources

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

Modulated Raman spectroscopy for enhanced cancer diagnosis at the cellular level [PDF]

, 2015
We thank the UK and Engineering and Physical Sciences Research Council through grant number EP/J01771X/1.Date of Acceptance: 24/05/2015Raman spectroscopy is emerging as a promising and novel biophotonics tool for non-invasive, real-time diagnosis of ...
De Luca, Anna Chiara, Michael Mazilu, Dholakia, Kishan, Mazilu, Michael, Anna De Luca, Anna Chiara De Luca, Kishan Dholakia, Dholakia K, De Luca A C, Mazilu M   +9 more
core   +1 more source